Background People with tuberculosis (TB) face multi-dimensional barriers when accessing
and engaging with care. There is evidence that providing psychosocial support within …

Tuberculosis (TB) has emerged as the leading infectious cause of death globally. New
paradigms are needed to reduce TB rates and mortality. Programs harnessing the potential …

Background Updated World Health Organization (WHO) treatment guidelines prioritize all-
oral drug-resistant tuberculosis (DR-TB) regimens. Several poorly tolerated drugs, such as …

Rationale Multi-drug-resistant tuberculosis (MDR-TB) poses a significant public health
challenge to the control and successful eradication of TB globally. Suboptimal treatment …

Background Health facility-based directly observed therapy (HF DOT) is the main strategy for
the management of patients with drug-resistant tuberculosis (DR TB) in Uganda, however …

Background Decentralization of Drug-Resistant Tuberculosis (DR-TB) services using
multilevel interventions was piloted in Akwa-Ibom and Oyo States of Nigeria, which had high …

Background Whole-genome sequencing (WGS)-based prediction of drug resistance in
Mycobacterium tuberculosis has the potential to guide clinical decisions in the design of …

Background Decentralized management approaches for multi-drug-resistant tuberculosis
(MDR TB) have shown improved treatment outcomes in patients. However, challenges …

The clinical complexity of co-managing drug-resistant TB and HIV, and the higher rate of
poor treatment outcomes in this population demand careful clinical management strategies …

Background: Tuberculosis (TB) patient management (TPM) is crucial to improve patient
compliance to treatment. The coverage of TPM delivered by TB dispensaries or Centers for …