Killer Ig-like receptors (KIRs): their role in NK cell modulation and developments leading to their clinical exploitation
Natural killer (NK) cells contribute to the first line of defense against viruses and to the
control of tumor growth and metastasis spread. The discovery of HLA class I specific …
control of tumor growth and metastasis spread. The discovery of HLA class I specific …
The application of natural killer cell immunotherapy for the treatment of cancer
K Rezvani, RH Rouce - Frontiers in immunology, 2015 - frontiersin.org
Natural killer (NK) cells are essential components of the innate immune system and play a
critical role in host immunity against cancer. Recent progress in our understanding of NK cell …
critical role in host immunity against cancer. Recent progress in our understanding of NK cell …
Multifunctional plant virus nanoparticles: An emerging strategy for therapy of cancer
Cancer therapy requires sophisticated treatment strategies to obtain the highest success.
Nanotechnology is enabling, revolutionizing, and multidisciplinary concepts to improve …
Nanotechnology is enabling, revolutionizing, and multidisciplinary concepts to improve …
HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses
Z Lin, AA Bashirova, M Viard, L Garner, M Quastel… - Nature …, 2023 - nature.com
Human leukocyte antigen (HLA)-E binds epitopes derived from HLA-A, HLA-B, HLA-C and
HLA-G signal peptides (SPs) and serves as a ligand for CD94/NKG2A and CD94/NKG2C …
HLA-G signal peptides (SPs) and serves as a ligand for CD94/NKG2A and CD94/NKG2C …
High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
HLA-E is a non-classical class I MHC protein involved in innate and adaptive immune
recognition. While recent studies have shown HLA-E can present diverse peptides to NK …
recognition. While recent studies have shown HLA-E can present diverse peptides to NK …
Human KIR repertoires: shaped by genetic diversity and evolution
AR Manser, S Weinhold, M Uhrberg - Immunological reviews, 2015 - Wiley Online Library
Killer cell immunoglobulin‐like receptors (KIR s) on natural killer (NK) cells are crucially
involved in the control of cancer development and virus infection by probing cells for proper …
involved in the control of cancer development and virus infection by probing cells for proper …
KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C
MM Naiyer, SA Cassidy, A Magri, V Cowton… - Science …, 2017 - science.org
Killer cell immunoglobulin-like receptors (KIRs) are rapidly evolving species-specific natural
killer (NK) cell receptors associated with protection against multiple different human viral …
killer (NK) cell receptors associated with protection against multiple different human viral …
Missing or altered self: human NK cell receptors that recognize HLA-C
HG Hilton, P Parham - Immunogenetics, 2017 - Springer
Natural killer (NK) cells are fast-acting and versatile lymphocytes that are critical effectors of
innate immunity, adaptive immunity, and placental development. Controlling NK cell function …
innate immunity, adaptive immunity, and placental development. Controlling NK cell function …
NK cell therapy for hematologic malignancies
RS Mehta, B Randolph, M Daher, K Rezvani - International journal of …, 2018 - Springer
Natural killer (NK) cells are part of the innate immune system and represent the first line of
defense against infections and tumors. In contrast to T cells, NK cells do not require prior …
defense against infections and tumors. In contrast to T cells, NK cells do not require prior …
A bird's eye view of NK cell receptor interactions with their MHC class I ligands
The surveillance of target cells by natural killer (NK) cells utilizes an ensemble of inhibitory
and activating receptors, many of which interact with major histocompatibility complex …
and activating receptors, many of which interact with major histocompatibility complex …