Acute myeloid leukemia (AML) establishes an immunosuppressive microenvironment that
favors leukemic proliferation. The immune-suppressive cytokines altered antigen …

The aim of this study was to explore the experiences of nurses providing end-of-life care to
patients with hematologic malignancies, in a hematology oncology setting, in an acute …

Objective Transporter associated with antigen processing protein (TAP) is a heterodimer
protein consist of TAP1 and TAP2, act a pivotal part in the immune surveillance. In recent …

Background Basal cell carcinoma (BCC) of the skin is the most common form of human
cancer, with more than 90% of tumours presenting with clear genetic activation of the …

Herpesviruses encode numerous immune evasion molecules that interfere with the immune
system, particularly with certain stages in the MHC class I antigen presentation pathway. In …

The regions in the genome that encode components of the immune system are often
featured by polymorphism, copy number variation, and segmental duplications. There is a …

Lung cancer is strongly associated with cigarette smoking; nevertheless some never-
smokers develop cancer. Immune eradication of cancer cells is dependent on …

TAP1 and TAP2 genes encode heterodimeric molecule involved in endogenous antigen
processing. The present study was undertaken to find out the possible association between …

Proteasome subunit beta types 8 and 9 (PSMB8, PSMB9) play critical roles in the human
leukocyte antigen class I (HLA I)-presenting system. Studies have suggested that …

The TAP1-TAP2 complex transports antigenic peptide substrates into the endoplasmic
reticulum (ER). In ER, the peptides are further processed and loaded on the major …