Cell deformability plays an important role in cellular processes and functions, including cell
growth and differentiation, as well as cell transfer and cell cycle. Measuring deformability at …

Mechanotherapy is proposed as a new option for cancer treatment. Increasing evidence
suggests that characteristic differences are present in the nuclear mechanics and …

Cytoskeletal filaments provide cells with mechanical stability and organization. The main key
players are actin filaments and microtubules governing a cell's response to mechanical …

This paper presents a comprehensive review of the development of the optical stretcher, a
powerful optofluidic device for single cell mechanical study by using optical force induced …

Cell lysis serves as an essential role in the sample preparation for intracellular material
extraction in lab-on-a-chip applications. However, recent microfluidic-based cell lysis chips …

The development of effective theranostic probes in cancer therapy is hampered due to
issues with selectivity and off-target toxicity. We report the selective LED-photothermal …

A substantial ion flow in a normally wet protein masks any other forms of signal transmission.
We use hysteresis and linear conduction (both are artifacts) as a marker to precisely wet a …

The mechanical properties of cells, tissues, and the surrounding extracellular matrix
environment play important roles in the process of cell adhesion and migration. In …

Cell contractility is mainly imagined as a force dipole-like interaction based on actin stress
fibers that pull on cellular adhesion sites. Here, we present a different type of contractility …

Understanding the physical mechanisms governing nuclear mechanics is important as it can
impact gene expression and development. However, how cell nuclei respond to external …