[HTML][HTML] Hydrogen sulfide regulates the redox state of soluble guanylate cyclase in CSE-/-mice corpus cavernosum microcirculation

MA Olivencia, E Esposito, V Brancaleone… - Pharmacological …, 2023‏ - Elsevier
The corpus cavernosum (CC) is a highly vascularized tissue and represents an excellent
example of microcirculation. Indeed, erectile dysfunction is considered an early index of …

Genetic prediction of modifiable lifestyle factors for erectile dysfunction

YJ **, YG Feng, YQ Bai, R Wen, HY Zhang… - Sexual …, 2024‏ - academic.oup.com
Background The causal relationship between certain lifestyle factors and erectile
dysfunction (ED) is still uncertain. Aim The study sought to investigate the causal effect of 9 …

Perinatal hypoxia augments contractile impact of NADPH oxidase-derived ROS in early postnatal rat arteries

VS Shateeva, SD Simonenko, MA Khlystova… - Pediatric …, 2024‏ - nature.com
Background Reactive oxygen species (ROS), including those produced by NADPH oxidase
(NOX), play an important vasomotor role, especially at early postnatal period. Mechanisms …

Role of interaction mode of phenanthrene derivatives as selective PDE5 inhibitors using molecular dynamics simulations and quantum chemical calculations

S Sainimnuan, A Chimprasit, S Hannongbua… - Molecular Diversity, 2024‏ - Springer
Abstract Phosphodiesterase type 5 (PDE5) inhibitors play a crucial role in blocking PDE5 to
improve erectile dysfunction (ED). However, most PDE5 drugs revealed side effects …

Vitamin D deficiency induces erectile dysfunction: role of superoxide

MA Olivencia, B Climent, B Barreira, D Morales-Cano… - bioRxiv, 2023‏ - biorxiv.org
Epidemiological studies suggest a relationship between vitamin D deficiency and erectile
dysfunction (ED) but its causal relationship and the mechanism involved are unclear. Here …