Cardiac–coronary interaction is fundamental to the function of the heart. As one of the
highest metabolic organs in the body, the cardiac oxygen demand is met by blood perfusion …

Computational, or in silico, models are an effective, noninvasive tool for investigating
cardiovascular function. These models can be used in the analysis of experimental and …

Pulmonary artery stenosis (PAS) often presents in children with congenital heart disease,
altering blood flow and pressure during critical periods of growth and development …

Background Integration of a patient's non-invasive imaging data in a digital twin (DT) of the
heart can provide valuable insight into the myocardial disease substrates underlying left …

Computational models that can predict growth and remodeling of the heart could have
important clinical applications. However, the time it takes to calibrate and run current models …

Towards a mathematical understanding of ventilator-induced lung injury in preterm rat pups
Page 170 Towards a Mathematical Understanding of Ventilator-Induced Lung Injury in Preterm …

Computational models provide an efficient paradigm for integrating and linking multiple
spatial and temporal scales. However, these models are difficult to parameterize and match …

The complexity of mathematical models describing respiratory mechanics has grown in
recent years, however, parameter identifiability of such models has only been studied in the …

Thoracoabdominal asynchrony (TAA), the asynchronous volume changes between the rib
cage and abdomen during breathing, is associated with respiratory distress, progressive …

Inhalation has become widely accepted as the optimal drug delivery mechanism for
respiratory diseases, which often requires targeting a particular region of the lung …