Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Fluorogenic probes for disease-relevant enzymes

J Zhang, X Chai, XP He, HJ Kim, J Yoon… - Chemical Society …, 2019 - pubs.rsc.org
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Advances in fluorescent probes for targeting organelles: Design strategies, applications and perspectives

M Zhu, W Li, L Sun, Z Lv, X Yang, Y Wang - Coordination Chemistry …, 2024 - Elsevier
Organelles, crucial components within eukaryotic cells, play a vital role in sustaining normal
physiological functions and cellular activities. The physiological role of a biomolecule in a …

Small molecule as fluorescent probes for monitoring intracellular enzymatic transformations

H Singh, K Tiwari, R Tiwari, SK Pramanik… - Chemical …, 2019 - ACS Publications
All cellular processes are the results of synchronized actions of several intracellular
biochemical pathways. Recent emphasis is to visualize such pathways using appropriate …

Recognition moieties of small molecular fluorescent probes for bioimaging of enzymes

X Wu, W Shi, X Li, H Ma - Accounts of chemical research, 2019 - ACS Publications
Conspectus Enzymes are a class of important substances for life, and their abnormal levels
are associated with many diseases. Thus, great progress has been made in the past decade …

1, 8-Naphthalimide based fluorescent sensors for enzymes

C Geraghty, C Wynne, RBP Elmes - Coordination Chemistry Reviews, 2021 - Elsevier
Fluorescent probes have long been valuable tools in the study of biological systems. With
the ever-expanding range of known enzymatic biomarkers for disease, it has never been …

Wearable wireless tyrosinase bandage and microneedle sensors: toward melanoma screening

B Ciui, A Martin, RK Mishra, B Brunetti… - Advanced …, 2018 - Wiley Online Library
Wearable bendable bandage‐based sensor and a minimally invasive microneedle
biosensor are described toward rapid screening of skin melanoma. These wearable …

In Situ Tyrosinase Monitoring by Wearable Microneedle Patch toward Clinical Melanoma Screening

X Huang, L Chen, T Sha, Y Lin, R Zeng, J Xu, S Chen… - ACS …, 2023 - ACS Publications
Despite the potential indicating role of tyrosinase (TYR) in cutaneous melanoma, how to
capture the real changes of TYR in suspicious skin remains a major challenge. Unlike the …

Fluorescent probes for visualizing ROS-associated proteins in disease

H Wang, X Wang, P Li, M Dong, SQ Yao, B Tang - Chemical Science, 2021 - pubs.rsc.org
Abnormal expression of proteins, including catalytic and expression dysfunction, is directly
related to the development of various diseases in living organisms. Reactive oxygen species …

In situ localization of enzyme activity in live cells by a molecular probe releasing a precipitating fluorochrome

HW Liu, K Li, XX Hu, L Zhu, Q Rong… - Angewandte Chemie …, 2017 - Wiley Online Library
Current enzyme‐responsive, fluorogenic probes fail to provide in situ information because
the released fluorophores tend to diffuse away from the reaction sites. The problem of …