Seasonal breeding is a remarkable adaptive feature, which allows animals to coordinate
physiological functions throughout the year. However, in the context of animal production, it …

This review considers three aspects of recent work on the role of KNDy neurons in GnRH
pulse generation in ruminants. First, work on basic mechanisms of pulse generation …

Kisspeptins are the product of the Kiss1 gene and potently stimulate GnRH secretion. In
sheep, Kiss1 mRNA-expressing cells are found in the arcuate nucleus (ARC) and dorsal …

The control of reproductive processes involves the integration of a number of factors from the
internal and external environment, with the final output signal of these processes being the …

The neuropeptide kisspeptin and its receptor, KiSS1R, govern the reproductive timeline of
mammals by triggering puberty onset and promoting ovulation by stimulating gonadotrophin …

The first ovulation induced by male effect in sheep during seasonal anoestrus usually results
in the development of a short cycle that can be avoided by progesterone priming before ram …

The discovery that kisspeptin was critical for normal fertility in humans ushered in a new
chapter in our understanding of the control of GnRH secretion. In this paper, we will review …

Kisspeptin cells appear to be the “missing link,” bridging the divide between levels of
gonadal steroids and feedback control of gonadotropin-releasing hormone (GnRH) …

Recent work has implicated stimulatory kisspeptin neurons in the arcuate nucleus (ARC) as
important for seasonal changes in reproductive function in sheep, but earlier studies support …

Kisspeptin (KISS1) is encoded by the KISS1 gene and was initially found to be a repressor
of metastasis. Natural mutations in the KISS1 receptor gene (KISS1R) were subsequently …