From energy perspective, with abundant polysaccharides (45–85%), the renewable
lignocellulosic is recognized as the 2nd generation feedstock for bioethanol and bio-based …

Polyethylene terephthalate (PET), the most abundantly produced polyester plastic, can be
depolymerized by the Ideonella sakaiensis PETase enzyme. Based on multiple PETase …

Glycosyltransferases (GTs) are carbohydrate-active enzymes that are encoded by the
genomes of organisms spanning all domains of life. GTs catalyze glycosidic bond formation …

The protein networks of cell-wall-biosynthesis assemblies are largely unknown. A key class
of enzymes in these assemblies is the lytic transglycosylases (LTs), of which eleven exist in …

Lignocellulose is a major component of vascular plant biomass. Its decomposition is crucial
for the terrestrial carbon cycle. Microorganisms are considered primary decomposers, but …

The red abalone (Haliotis rufescens) represents North America's most important aquaculture
species. Its hepatopancreas is rich in cellulases and other polysaccharide-degrading …

Spatial confinement is widely employed by nature to attain unique efficiency in controlling
chemical reactions. Notable examples are enzymes, which selectively bind reactants and …

Biorefinery processes for converting lignocellulosic biomass to fuels and chemicals proceed
via an integrated series of steps. Biomass is first pretreated and deconstructed using …

Glycoside hydrolases (GH) cleave carbohydrate glycosidic bonds and play pivotal roles in
living organisms and in many industrial processes. Unlike acid-catalyzed hydrolysis of …

This Perspective reviews the use of Transition Path Sampling methods to study
enzymatically catalyzed chemical reactions. First applied by our group to an enzymatic …