Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
[HTML][HTML] Current perspectives on the beneficial effects of soybean isoflavones and their metabolites for humans
IS Kim - Antioxidants, 2021 - mdpi.com
Soybeans are rich in proteins and lipids and have become a staple part of the human diet.
Besides their nutritional excellence, they have also been shown to contain various functional …
Besides their nutritional excellence, they have also been shown to contain various functional …
[HTML][HTML] Cancer prevention and therapy through the modulation of the tumor microenvironment
Cancer arises in the context of an in vivo tumor microenvironment. This microenvironment is
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …
[HTML][HTML] Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents
Cancer is one of the leading causes of death and significantly burdens the healthcare
system. Due to its prevalence, there is undoubtedly an unmet need to discover novel …
system. Due to its prevalence, there is undoubtedly an unmet need to discover novel …
Comprehensive and critical view on the anti-inflammatory and immunomodulatory role of natural phenolic antioxidants
The immune response encompasses innate and adaptive immunity, each with distinct and
specific activities. The innate immune system is constituted by phagocytic cells …
specific activities. The innate immune system is constituted by phagocytic cells …
Evaluation of the antitumor immune responses of probiotic Bifidobacterium bifidum in human papillomavirus-induced tumor model
As of present, a number of studies have shown anti-cancer effects of different strains of
probiotics, but the precise host immunological mechanisms of these antitumor effects remain …
probiotics, but the precise host immunological mechanisms of these antitumor effects remain …
[HTML][HTML] A multi-targeted approach to suppress tumor-promoting inflammation
Cancers harbor significant genetic heterogeneity and patterns of relapse following many
therapies are due to evolved resistance to treatment. While efforts have been made to …
therapies are due to evolved resistance to treatment. While efforts have been made to …
[HTML][HTML] Effects of genistein supplementation on genome‑wide DNA methylation and gene expression in patients with localized prostate cancer
B Bilir, NV Sharma, J Lee… - International …, 2017 - spandidos-publications.com
Epidemiological studies have shown that dietary compounds have significant effects on
prostate carcinogenesis. Among dietary agents, genistein, the major isoflavone in soybean …
prostate carcinogenesis. Among dietary agents, genistein, the major isoflavone in soybean …
Potential mechanisms of plant-derived natural products in the treatment of cervical cancer
M He, L **a, J Li - Biomolecules, 2021 - mdpi.com
Cervical cancer is the second most common gynecological malignancy globally; it seriously
endangers women's health because of its high morbidity and mortality. Conventional …
endangers women's health because of its high morbidity and mortality. Conventional …
A Comprehensive Review of Genistein's Effects in Preclinical Models of Cervical Cancer
Simple Summary Cervical cancer is the fourth most commonly diagnosed cancer among
women worldwide. While treatments exist to stop growth of cervical cancer in humans, they …
women worldwide. While treatments exist to stop growth of cervical cancer in humans, they …