Targeting cytokine and chemokine signaling pathways for cancer therapy
Cytokines are critical in regulating immune responses and cellular behavior, playing dual
roles in both normal physiology and the pathology of diseases such as cancer. These …
roles in both normal physiology and the pathology of diseases such as cancer. These …
SARS-CoV-2 infection: The role of cytokines in COVID-19 disease
VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …
The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19
C Schultheiß, E Willscher, L Paschold, C Gottschick… - Cell Reports …, 2022 - cell.com
Post-acute sequelae of COVID-19 (PASC) is emerging as global problem with unknown
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …
A review of SARS-CoV-2 and the ongoing clinical trials
YF Tu, CS Chien, AA Yarmishyn, YY Lin… - International journal of …, 2020 - mdpi.com
The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in
Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a …
Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a …
COVID-19 and oxidative stress
BV Chernyak, EN Popova, AS Prikhodko… - Biochemistry …, 2020 - Springer
Pathogenesis of the novel coronavirus infection COVID-19 is the subject of active research
around the world. COVID-19 caused by the SARS-CoV-2 is a complex disease in which …
around the world. COVID-19 caused by the SARS-CoV-2 is a complex disease in which …
Microglia in the neuroinflammatory pathogenesis of Alzheimer's disease and related therapeutic targets
Y Cai, J Liu, B Wang, M Sun, H Yang - Frontiers in immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease worldwide,
characterized by progressive neuron degeneration or loss due to excessive accumulation of …
characterized by progressive neuron degeneration or loss due to excessive accumulation of …
Crosstalk of inflammatory cytokines within the breast tumor microenvironment
O Habanjar, R Bingula, C Decombat… - International journal of …, 2023 - mdpi.com
Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …
JAK-STAT signaling: a double-edged sword of immune regulation and cancer progression
KL Owen, NK Brockwell, BS Parker - Cancers, 2019 - mdpi.com
Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling mediates
almost all immune regulatory processes, including those that are involved in tumor cell …
almost all immune regulatory processes, including those that are involved in tumor cell …
Cytokine release syndrome
A Shimabukuro-Vornhagen, P Gödel… - … for immunotherapy of …, 2018 - Springer
During the last decade the field of cancer immunotherapy has witnessed impressive
progress. Highly effective immunotherapies such as immune checkpoint inhibition, and T …
progress. Highly effective immunotherapies such as immune checkpoint inhibition, and T …
Diabetic macular edema: current understanding, molecular mechanisms and therapeutic implications
Diabetic retinopathy (DR), with increasing incidence, is the major cause of vision loss and
blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the …
blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the …