Validation and opportunities of electrocardiographic imaging: from technical achievements to clinical applications

M Cluitmans, DH Brooks, R MacLeod, O Dössel… - Frontiers in …, 2018 - frontiersin.org
Electrocardiographic imaging (ECGI) reconstructs the electrical activity of the heart from a
dense array of body-surface electrocardiograms and a patient-specific heart-torso geometry …

Diagnosis and management of arrhythmogenic right ventricular cardiomyopathy

L Alblaihed, C Kositz, WJ Brady, T Al-Salamah… - The American Journal of …, 2023 - Elsevier
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic disorder of the
myocardium that can lead to ventricular arrhythmia and sudden cardiac death. The condition …

Performance and limitations of noninvasive cardiac activation map**

J Duchateau, F Sacher, T Pambrun, N Derval… - Heart rhythm, 2019 - Elsevier
Background Activation map** using noninvasive electrocardiographic imaging (ECGi) has
recently been used to describe the physiology of different cardiac abnormalities. These …

Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2–Deficient Hearts

CJM Van Opbergen, N Bagwan, SR Maurya, JC Kim… - Circulation, 2022 - Am Heart Assoc
Background: Exercise training, and catecholaminergic stimulation, increase the incidence of
arrhythmic events in patients affected with arrhythmogenic right ventricular cardiomyopathy …

Electrocardiographic imaging for cardiac arrhythmias and resynchronization therapy

H Pereira, S Niederer, CA Rinaldi - 2020 - academic.oup.com
Use of the 12-lead electrocardiogram (ECG) is fundamental for the assessment of heart
disease, including arrhythmias, but cannot always reveal the underlying mechanism or the …

[HTML][HTML] Harnessing 12-lead ECG and MRI data to personalise repolarisation profiles in cardiac digital twin models for enhanced virtual drug testing

J Camps, ZJ Wang, R Doste, LA Berg, M Holmes… - Medical Image …, 2025 - Elsevier
Cardiac digital twins are computational tools capturing key functional and anatomical
characteristics of patient hearts for investigating disease phenotypes and predicting …

Robotic manipulation of cardiomyocytes to identify gap junction modifiers for arrhythmogenic cardiomyopathy

W Dou, G Shan, Q Zhao, M Malhi, A Jiang, Z Zhang… - Science Robotics, 2024 - science.org
Arrhythmogenic cardiomyopathy (ACM) is a leading cause of sudden cardiac death among
young adults. Aberrant gap junction remodeling has been linked to disease-causative …

Noninvasive map** of the electrophysiological substrate in cardiac amyloidosis and its relationship to structural abnormalities

M Orini, AJ Graham, A Martinez‐Naharro… - Journal of the …, 2019 - Am Heart Assoc
Background The relationship between structural pathology and electrophysiological
substrate in cardiac amyloidosis is unclear. Differences between light‐chain (AL) and …

Epicardial origin of cardiac arrhythmias: clinical evidences and pathophysiology

C Chaumont, N Suffee, E Gandjbakhch… - Cardiovascular …, 2022 - academic.oup.com
Recent developments in imaging, map**, and ablation techniques have shown that the
epicardial region of the heart is a key player in the occurrence of ventricular arrhythmic …

Electrophysiological characterization of subclinical and overt hypertrophic cardiomyopathy by magnetic resonance imaging-guided electrocardiography

G Joy, LR Lopes, M Webber, AM Ardissino… - Journal of the American …, 2024 - jacc.org
Background Ventricular arrhythmia in hypertrophic cardiomyopathy (HCM) relates to
adverse structural change and genetic status. Cardiovascular magnetic resonance (CMR) …