Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: considerations during the COVID-19 crisis
The coronavirus-disease 2019 (COVID-19) was announced as a global pandemic by the
World Health Organization. Challenges arise concerning how to optimally support the …
World Health Organization. Challenges arise concerning how to optimally support the …
Dietary regulation in health and disease
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …
in molecular medicine and clinical trials have demonstrated that adequate nutrition …
Differential peripheral immune signatures elicited by vegan versus ketogenic diets in humans
Nutrition has broad impacts on all physiological processes. However, how nutrition affects
human immunity remains largely unknown. Here we explored the impact of a dietary …
human immunity remains largely unknown. Here we explored the impact of a dietary …
Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19
Anorexia and fasting are host adaptations to acute infection, and induce a metabolic switch
towards ketogenesis and the production of ketone bodies, including β-hydroxybutyrate …
towards ketogenesis and the production of ketone bodies, including β-hydroxybutyrate …
[HTML][HTML] Ketolysis drives CD8+ T cell effector function through effects on histone acetylation
KM Luda, J Longo, SM Kitchen-Goosen, LR Duimstra… - Immunity, 2023 - cell.com
Environmental nutrient availability influences T cell metabolism, impacting T cell function
and sha** immune outcomes. Here, we identified ketone bodies (KBs)—including β …
and sha** immune outcomes. Here, we identified ketone bodies (KBs)—including β …
[HTML][HTML] Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade
Limited experimental evidence bridges nutrition and cancer immunosurveillance. Here, we
show that ketogenic diet (KD)—or its principal ketone body, 3-hydroxybutyrate (3HB), most …
show that ketogenic diet (KD)—or its principal ketone body, 3-hydroxybutyrate (3HB), most …
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments
N Lopes, C McIntyre, S Martin, M Raverdeau… - Nature …, 2021 - nature.com
Metabolic programming controls immune cell lineages and functions, but little is known
about γδ T cell metabolism. Here, we found that γδ T cell subsets making either interferon-γ …
about γδ T cell metabolism. Here, we found that γδ T cell subsets making either interferon-γ …
Control of immunity via nutritional interventions
Nutrition affects all physiological processes including those linked to the development and
function of our immune system. Here, we discuss recent evidence and emerging concepts …
function of our immune system. Here, we discuss recent evidence and emerging concepts …
Interleukin-17 as a key player in neuroimmunometabolism
Abstract In mammals, interleukin (IL)-17 cytokines are produced by innate and adaptive
lymphocytes. However, the IL-17 family has widespread expression throughout evolution …
lymphocytes. However, the IL-17 family has widespread expression throughout evolution …
High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 infection
Fever is a common symptom of influenza and coronavirus disease 2019 (COVID-19), yet its
physiological role in host resistance to viral infection remains less clear. Here, we …
physiological role in host resistance to viral infection remains less clear. Here, we …