Methotrexate (MTX) is one of the most effective and widely used drugs in the management of
autoimmune and dermatological diseases. Rheumatoid arthritis and psoriasis patients who …

Background Drug-induced liver injury (DILI) is the most challenging and thought-provoking
liver problem for hepatologists owing to unregulated medication usage in medical practices …

Methotrexate is a key component of the treatment of inflammatory rheumatic diseases and
the mainstay of therapy in rheumatoid arthritis. Hepatotoxicity has long been a concern for …

Background Ginkgo biloba leaves (GB Ls), as an herbal dietary supplement and a traditional
Chinese medicine, have been used in treating diseases for hundred years. Recently …

Isoginkgetin (ISO), a natural biflavonoid, exhibited cytotoxic activity against several types of
cancer cells. However, its effects on hepatocellular carcinoma (HCC) cells and mechanism …

Aortic aneurysm is a vascular disease characterized by irreversible vasodilatation that can
lead to dissection and rupture of the aortic aneurysm, a life-threatening condition. Thoracic …

Aims This study investigates the therapeutic potential of Vilda in a NASH model with liver
fibrosis and elucidates the underlying molecular mechanisms. Main methods To induce …

Methotrexate (MTX) is an efficient chemotherapeutic agent for treating various malignancies
and autoimmune diseases. However, the long-term use of MTX can result in hepatotoxicity …

Methotrexate is a familiar chemotherapeutic preferred in a wide range of clinical fields such
as leukemia, psoriasis, rheumatoid arthritis, neoplastic and autoimmune disorders …

Hinokiflavone (HF), classified as a flavonoid, is a main bioactive compound in Platycladus
orientalis and Selaginella. HF exhibits activities including anti-HIV, anti-inflammatory …