The hypothalamus-pituitary-gonad axis: tales of mice and men
A Kaprara, IT Huhtaniemi - Metabolism, 2018 - Elsevier
Reproduction is controlled by the hypothalamic-pituitary-gonadal (HPG) axis. Gonadotropin-
releasing hormone (GnRH) neurons play a central role in this axis through production of …
releasing hormone (GnRH) neurons play a central role in this axis through production of …
Evolution of GnRH: diving deeper
GJ Roch, ER Busby, NM Sherwood - General and comparative …, 2011 - Elsevier
Gonadotropin-releasing hormone (GnRH) plays a central role in vertebrate reproduction.
The evolutionary origin of this neuropeptide and its receptor is not obvious, but the advent of …
The evolutionary origin of this neuropeptide and its receptor is not obvious, but the advent of …
The role of gonadotropin-releasing hormone in cancer cell proliferation and metastasis
C Gründker, G Emons - Frontiers in endocrinology, 2017 - frontiersin.org
In several human malignant tumors of the urogenital tract, including cancers of the
endometrium, ovary, urinary bladder, and prostate, it has been possible to identify …
endometrium, ovary, urinary bladder, and prostate, it has been possible to identify …
From nose to brain: development of gonadotrophin‐releasing hormone‐1 neurones
S Wray - Journal of neuroendocrinology, 2010 - Wiley Online Library
Gonadotrophin‐releasing hormone‐1 (GnRH‐1) is essential for mammalian reproduction,
controlling release of gonadotrophins from the anterior pituitary. GnRH‐1 neurones migrate …
controlling release of gonadotrophins from the anterior pituitary. GnRH‐1 neurones migrate …
GnRH, anosmia and hypogonadotropic hypogonadism–where are we?
Gonadotropin releasing hormone (GnRH) neurons originate the nasal placode and migrate
into the brain during prenatal development. Once within the brain, these cells become …
into the brain during prenatal development. Once within the brain, these cells become …
GnRH receptors and peptides: skating backward
GJ Roch, ER Busby, NM Sherwood - General and comparative …, 2014 - Elsevier
Gonadotropin-releasing hormone (GnRH) and its receptor are essential for reproduction in
vertebrates. Although there are three major types of GnRH peptides and two major types of …
vertebrates. Although there are three major types of GnRH peptides and two major types of …
Origin and evolution of the neuroendocrine control of reproduction in vertebrates, with special focus on genome and gene duplications
S Dufour, B Quérat, H Tostivint… - Physiological …, 2020 - journals.physiology.org
In humans, as in the other mammals, the neuroendocrine control of reproduction is ensured
by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are …
by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are …
Genetic identification of GnRH receptor neurons: a new model for studying neural circuits underlying reproductive physiology in the mouse brain
GnRH signaling regulates reproductive physiology in vertebrates via the hypothalamic-
pituitary-gonadal axis. In addition, GnRH signaling has been postulated to act on the brain …
pituitary-gonadal axis. In addition, GnRH signaling has been postulated to act on the brain …
Highlights of neuroanatomical discoveries of the mammalian gonadotropin‐releasing hormone system
The anatomy and morphology of gonadotropin‐releasing hormone (GnRH) neurons makes
them both a joy and a challenge to investigate. They are a highly unique population of …
them both a joy and a challenge to investigate. They are a highly unique population of …
The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia
K Skrapits, M Sárvári, I Farkas, B Göcz, S Takács… - Elife, 2021 - elifesciences.org
Human reproduction is controlled by~ 2000 hypothalamic gonadotropin-releasing hormone
(GnRH) neurons. Here, we report the discovery and characterization of additional~ 150,000 …
(GnRH) neurons. Here, we report the discovery and characterization of additional~ 150,000 …