Raman spectroscopy as a process analytical technology for pharmaceutical manufacturing and bioprocessing

KA Esmonde-White, M Cuellar, C Uerpmann… - Analytical and …, 2017 - Springer
Abstract Adoption of Quality by Design (QbD) principles, regulatory support of QbD, process
analytical technology (PAT), and continuous manufacturing are major factors effecting new …

[HTML][HTML] Raman spectroscopy in pharmaceutical product design

A Paudel, D Raijada, J Rantanen - Advanced drug delivery reviews, 2015 - Elsevier
Almost 100 years after the discovery of the Raman scattering phenomenon, related
analytical techniques have emerged as important tools in biomedical sciences. Raman …

Recent advances in low-frequency Raman spectroscopy for pharmaceutical applications

K Bērziņš, SJ Fraser-Miller, KC Gordon - International journal of …, 2021 - Elsevier
Low-frequency Raman (LFR) spectroscopy probes vibrational modes related to long-range
order (ie, crystallinity) that can provide unique information on the solid-state/structural …

Terahertz time-domain and low-frequency Raman spectroscopy of organic materials

EPJ Parrott, JA Zeitler - Applied spectroscopy, 2015 - journals.sagepub.com
With the ongoing proliferation of terahertz time-domain instrumentation from semiconductor
physics into applied spectroscopy over the past decade, measurements at terahertz …

Enamel white spot lesions can remineralise using bio-active glass and polyacrylic acid-modified bio-active glass powders

H Milly, F Festy, TF Watson, I Thompson, A Banerjee - Journal of dentistry, 2014 - Elsevier
Objective To evaluate the potential of bio-active glass (BAG) powder and BAG containing
polyacrylic acid (PAA-BAG) to remineralise enamel white spot lesions (WSL). Methods 32 …

Recent progress of structural study of polymorphic pharmaceutical drugs

K Higashi, K Ueda, K Moribe - Advanced drug delivery reviews, 2017 - Elsevier
This review considers advances in the understanding of active pharmaceutical ingredient
polymorphism since around 2010 mainly from a structural view point, with a focus on twelve …

Polymorph characterization of active pharmaceutical ingredients (APIs) using low-frequency Raman spectroscopy

PJ Larkin, M Dabros, B Sarsfield, E Chan… - Applied …, 2014 - journals.sagepub.com
Polymorph detection, identification, and quantitation in crystalline materials are of great
importance to the pharmaceutical industry. Vibrational spectroscopic techniques used for …

[HTML][HTML] Machine learning of Raman spectra predicts drug release from polysaccharide coatings for targeted colonic delivery

Y Abdalla, LE McCoubrey, F Ferraro… - Journal of Controlled …, 2024 - Elsevier
Colonic drug delivery offers numerous pharmaceutical opportunities, including direct access
to local therapeutic targets and drug bioavailability benefits arising from the colonic …

A review of pharmaceutical robot based on hyperspectral technology

X Su, Y Wang, J Mao, Y Chen, AT Yin, B Zhao… - Journal of intelligent & …, 2022 - Springer
The quality and safety of medicinal products are related to patients' lives and health.
Therefore, quality inspection takes a key role in the pharmaceutical industry. Most of the …

Raman spectroscopy and its plasmon‐enhanced counterparts: A toolbox to probe protein dynamics and aggregation

AK Dhillon, A Sharma, V Yadav, R Singh… - Wiley …, 2024 - Wiley Online Library
Protein unfolding and aggregation are often correlated with numerous diseases such as
Alzheimer's, Parkinson's, Huntington's, and other debilitating neurological disorders. Such …