The emergent outbreak of coronavirus disease 2019 (COVID-19) has caused a global
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are …

The article focuses on cytokine storm syndrome which is a diverse set of conditions unified
by a clinical phenotype of systemic inflammation, multi-organ failure and hyperferritinemia …

Objective Because it has no unique clinical, biologic, or histologic features, reactive
hemophagocytic syndrome may be difficult to distinguish from other diseases such as …

Objective To describe the clinical, laboratory, and histopathologic features, current
treatment, and outcome of patients with macrophage activation syndrome (MAS) …

Guidelines and recommendations developed and/or endorsed by the American College of
Rheumatology (ACR) are intended to provide guidance for particular patterns of practice …

Macrophage activation syndrome (MAS), a form of secondary hemophagocytic
lymphohistiocytosis, is a frequently fatal complication of a variety of pediatric inflammatory …

Systemic lupus erythematosus (SLE) is an autoimmune disease that attacks almost every
organ. The condition mostly happens to adults but is also found in children, and the latter …

Childhood-onset systemic lupus erythematosus (cSLE) is a rare, multisystem and potentially
life-threatening autoimmune disorder with significant associated morbidity. Evidence-based …

Rheumatic diseases are frequent chronic conditions that impose a great burden to society in
terms of losses in quality of life and cumbersome dependency1. Although they are …

Macrophage activation syndrome (MAS) is the name given to secondary hemophagocytic
lymphohistiocytosis (sHLH) associated with rheumatic diseases. Previously, MAS has been …