Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Bioconjugates are multifunctional constructs in which biomolecules like peptides, proteins,
vitamins and nucleic acids are endowed with the properties of specific payloads. These …

Triclosan is a broad-spectrum antibacterial and antifungal agent,, which acts by previously
undetermined mechanisms, that is used in products such as antiseptic soaps, toothpastes …

Triclosan (TCS), a lipophilic broad-spectrum biocide is widely used in personal care, acrylic,
veterinary, medical and household products. It has been observed to be present in aquatic …

▪ Abstract The type II fatty acid synthetic pathway is the principal route for the production of
membrane phospholipid acyl chains in bacteria and plants. The reaction sequence is …

The entire pathway of palmitate synthesis from malonyl-CoA in mammals is catalyzed by a
single, homodimeric, multifunctional protein, the fatty acid synthase. Each subunit contains …

Membrane lipid homeostasis is a vital facet of bacterial cell physiology. For decades,
research in bacterial lipid synthesis was largely confined to the Escherichia coli model …

The preferred antitubercular drug isoniazid specifically targets a long-chain enoyl-acyl
carrier protein reductase (InhA), an enzyme essential for mycolic acid biosynthesis in …

Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at
the enoyl-acyl carrier protein reductase (FabI) step. Resistance to triclosan inEscherichia …

Tuberculosis is today amongst the worldwide health threats. As resistant strains of
Mycobacterium tuberculosis have slowly emerged, treatment failure is too often a fact …