Chemotherapy in patients with early breast cancer: clinical overview and management of long-term side effects

P Di Nardo, C Lisanti, M Garutti, S Buriolla… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Neo/adjuvant therapy for early-stage breast cancer has become increasingly
common in the last few decades; as a consequence, the number of breast cancer survivors …

Cognitive impairment associated with cancer: a brief review

JC Pendergrass, SD Targum… - Innovations in clinical …, 2018 - pmc.ncbi.nlm.nih.gov
This brief review explores the areas of cognitive impairment that have been observed in
cancer patients and survivors, the cognitive assessment tools used, and the management of …

Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial

PD Brown, S Pugh, NN Laack, JS Wefel… - Neuro …, 2013 - academic.oup.com
Background To determine the protective effects of memantine on cognitive function in
patients receiving whole-brain radiotherapy (WBRT). Methods Adult patients with brain …

Radiation-induced brain injury: a review

D Greene-Schloesser, ME Robbins, AM Peiffer… - Frontiers in …, 2012 - frontiersin.org
Approximately 100,000 primary and metastatic brain tumor patients/year in the US survive
long enough (> 6 months) to experience radiation-induced brain injury. Prior to 1970, the …

Malignant gliomas in adults

PY Wen, S Kesari - New England Journal of Medicine, 2008 - Mass Medical Soc
Malignant gliomas, the most common type of primary brain tumor in adults, are associated
with disproportionate cancer-related morbidity and mortality. Recently, there have been …

European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma

A Pace, L Dirven, JAF Koekkoek, H Golla… - The Lancet …, 2017 - thelancet.com
Patients with glioma present with complex palliative care needs throughout their disease
trajectory. The life-limiting nature of gliomas and the presence of specific symptoms related …

Distress management

JC Holland, B Andersen, WS Breitbart… - Journal of the National …, 2013 - jnccn.org
The integration of psychosocial care into the routine care of all patients with cancer is
increasingly being recognized as the new standard of care. These NCCN Clinical Practice …

Donepezil for irradiated brain tumor survivors: a phase III randomized placebo-controlled clinical trial

SR Rapp, LD Case, A Peiffer, MM Naughton… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Neurotoxic effects of brain irradiation include cognitive impairment in 50% to 90%
of patients. Prior studies have suggested that donepezil, a neurotransmitter modulator, may …

CNS complications of radiotherapy and chemotherapy

C Soussain, D Ricard, JR Fike, JJ Mazeron… - The lancet, 2009 - thelancet.com
Treatment-induced CNS toxicity remains a major cause of morbidity in patients with cancer.
Advances in the design of safe radiation procedures have been counterbalanced by …

Neurocognitive function of patients with brain metastasis who received either whole brain radiotherapy plus stereotactic radiosurgery or radiosurgery alone

H Aoyama, M Tago, N Kato, T Toyoda, M Kenjyo… - International Journal of …, 2007 - Elsevier
PURPOSE: To determine how the omission of whole brain radiotherapy (WBRT) affects the
neurocognitive function of patients with one to four brain metastases who have been treated …