Implant-associated infection (IAI) is increasingly emerging as a serious threat with the
massive application of biomaterials. Bacteria attached to the surface of implants are often …

The increasing prevalence of multidrug-resistant bacterial infections necessitates the
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …

Over the past few decades, there has been a tremendous increase in the utilization of
therapeutic peptides. Therapeutic peptides are usually administered via the parenteral …

The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

With the increasing prevalence of multidrug resistant (MDR) bacteria, there is a need to
design synthetic antimicrobial peptides (AMPs) that are effective and selective for bacteria …

Bacterial resistance is a problem that is giving serious cause for concern because bacterial
strains such as Acinetobacter baumannii and Pseudomonas aeruginosa are difficult to treat …

Innate defense regulator-1002 (IDR-1002) is a synthetic peptide with promising
immunomodulatory and antibiofilm properties. An appreciable body of work exists around its …

Synthetic antibacterial and anti-biofilm peptide (SAAP)-148 was developed to combat
bacterial infections not effectively treatable with current antibiotics. SAAP-148 is highly …

Background Given the rising number of multidrug-resistant (MDR) bacteria, there is a need
to design synthetic antimicrobial peptides (AMPs) that are highly active, non-hemolytic, and …

The antimicrobial resistance crisis calls for the discovery and production of new
antimicrobials. Host defense peptides (HDPs) are small proteins with potent antibacterial …