Vaccine-like nanomedicine for cancer immunotherapy

Y Yi, M Yu, W Li, D Zhu, L Mei, M Ou - Journal of Controlled Release, 2023 - Elsevier
The successful clinical application of immune checkpoint blockade (ICB) and chimeric
antigen receptor T cells (CAR-T) therapeutics has attracted extensive attention to …

Self-driven nanoprodrug platform with enhanced ferroptosis for synergistic photothermal-IDO immunotherapy

P Huang, Y Yang, W Wang, Z Li, N Gao, H Chen… - Biomaterials, 2023 - Elsevier
Insufficient immune stimulation and stubborn immune resistance are the critical factors
limiting tumor immunotherapy. Here, we report a multifunctional nanoprodrug platform with …

[HTML][HTML] Advances in the delivery of anticancer drugs by nanoparticles and chitosan-based nanoparticles

J Prieložná, V Mikušová, P Mikuš - International Journal of Pharmaceutics …, 2024 - Elsevier
Cancer is the leading cause of death globally, and conventional treatments have limited
efficacy with severe side effects. The use of nanotechnology has the potential to reduce the …

Controlled phase transition of the onion-like carbon nanostructure for photothermal cancer therapy

Y Feng, S Lu, Q Zhao, T Sun, Y Shi, G Gao… - ACS Applied Nano …, 2024 - ACS Publications
Carbon-based nanomaterials are viewed as preferred candidates as photothermal agents in
tumor photothermal therapy due to their tailored structure and excellent biocompatibility …

NIR-light-triggered delivery of doxorubicin-loaded PLGA nanoparticles for synergistic cancer therapy on DMBA/TPA induced tumor-bearing mice

TZ Khan, SM Newaj, A Rahman, R Tabassum… - Materials …, 2023 - pubs.rsc.org
In this study, we developed NIR-light responsive poly (lactic-co-glycolic acid)(PLGA)
nanoparticles (NPs) by incorporating the ICG dye for the local delivery of small-molecule …

[HTML][HTML] Mn-phenolic networks as synergistic carrier for STING agonists in tumor immunotherapy

Y Meng, J Huang, J Ding, H Zhou, Y Li, W Zhou - Materials Today Bio, 2024 - Elsevier
The cGAS-STING pathway holds tremendous potential as a regulator of immune responses,
offering a means to reshape the tumor microenvironment and enhance tumor …

Integration of tumor elimination and tissue regeneration via selective manipulation of physiological microenvironments based on intelligent nanocomposite hydrogel …

L Chen, T Yang, L Weng, X Chang, J Liu… - Advanced Functional …, 2023 - Wiley Online Library
Tumor residue and tissue damage normally occurred after surgical treatment of malignant
melanoma, and the effective postoperative therapy is still a challenge because the treatment …

Porous Titanium Scaffolds with Mechanoelectrical Conversion and Photothermal Function: A Win‐Win Strategy for Bone Reconstruction of Tumor‐Resected Defects

Z Tang, D Yu, S Bao, C Li, H Wu… - Advanced …, 2024 - Wiley Online Library
Bone metastases severely threaten the lives of patients. Although surgical treatment
combined with adjuvant chemotherapy significantly improves the survival rate of patients …

[HTML][HTML] Tumor microenvironment-responsive gold nanodendrites for nanoprobe-based single-cell Raman imaging and tumor-targeted chemo-photothermal therapy

Y Shuai, Q Bao, H Yue, J Wang, T Yang, Q Wan… - Smart Materials in …, 2023 - Elsevier
Nanodendrite particles (NDs) with densely branched structures and biomimetic architectures
have exhibited great promise in tumor therapy owing to their prolonged in vivo circulation …