Incongruence in the phylogenomics era

JL Steenwyk, Y Li, X Zhou, XX Shen… - Nature Reviews Genetics, 2023 - nature.com
Genome-scale data and the development of novel statistical phylogenetic approaches have
greatly aided the reconstruction of a broad sketch of the tree of life and resolved many of its …

The promise and pitfalls of synteny in phylogenomics

JL Steenwyk, N King - PLoS Biology, 2024 - journals.plos.org
Reconstructing the tree of life remains a central goal in biology. Early methods, which relied
on small numbers of morphological or genetic characters, often yielded conflicting …

Origin of fungal hybrids with pathogenic potential from warm seawater environments

V Del Olmo, V Mixão, R Fotedar, E Saus… - Nature …, 2023 - nature.com
Hybridisation is a common event in yeasts often leading to genomic variability and
adaptation. The yeast Candida orthopsilosis is a human-associated opportunistic pathogen …

Interspecific hybridization as a driver of fungal evolution and adaptation

J Steensels, B Gallone, KJ Verstrepen - Nature Reviews Microbiology, 2021 - nature.com
Cross-species gene transfer is often associated with bacteria, which have evolved several
mechanisms that facilitate horizontal DNA exchange. However, the increased availability of …

Intraspecific diploidization of a halophyte root fungus drives heterosis

Z Li, Z Zhu, K Qian, B Tang, B Han, Z Zhong… - Nature …, 2024 - nature.com
How organisms respond to environmental stress is a key topic in evolutionary biology. This
study focused on the genomic evolution of Laburnicola rhizohalophila, a dark-septate …

Genomic diversity of the pathogenic fungus Aspergillus fumigatus in Japan reveals the complex genomic basis of azole resistance

X He, Y Kusuya, D Hagiwara, T Toyotome… - Communications …, 2024 - nature.com
Aspergillus fumigatus is a pathogenic fungus with a global distribution. The emergence of
azole-resistant A. fumigatus (AR Af) other than the TR-mutants is a problem in Japan …

Evolutionary origin and population diversity of a cryptic hybrid pathogen

JL Steenwyk, S Knowles, RW Bastos… - Nature …, 2024 - nature.com
Cryptic fungal pathogens pose disease management challenges due to their morphological
resemblance to known pathogens. Here, we investigated the genomes and phenotypes of …

Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence Across Aspergillus Species

JL Steenwyk, ME Mead, SL Knowles, HA Raja… - Genetics, 2020 - academic.oup.com
Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of
Virulence Across Aspergillus Species | Genetics | Oxford Academic Skip to Main Content …

Know the enemy and know yourself: Addressing cryptic fungal pathogens of humans and beyond

JL Steenwyk, A Rokas, GH Goldman - PLoS Pathogens, 2023 - journals.plos.org
“If you know the enemy and know yourself, you need not fear the result of a hundred battles.
If you know yourself but not the enemy, for every victory gained you will also suffer a defeat …

[HTML][HTML] Hybrids unleashed: exploring the emergence and genomic insights of pathogenic yeast hybrids

V Del Olmo, T Gabaldón - Current Opinion in Microbiology, 2024 - Elsevier
Highlights•Hybridisation is the crossing of divergent lineages.•Hybridisation in pervasive in
Saccharomycotina yeasts.•It is a source of genetic diversity, shapes evolution and …