Chemically modified and conjugated antimicrobial peptides against superbugs

W Li, F Separovic, NM O'Brien-Simpson… - Chemical Society …, 2021‏ - pubs.rsc.org
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021‏ - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Antimicrobial peptides: from design to clinical application

C Zhang, M Yang - Antibiotics, 2022‏ - mdpi.com
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …

Antimicrobial peptides: a new frontier in antifungal therapy

G Buda De Cesare, SA Cristy, DA Garsin, MC Lorenz - MBio, 2020‏ - journals.asm.org
Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

Mycobacterium tuberculosis cell-wall and antimicrobial peptides: a mission impossible?

YM Jacobo-Delgado, A Rodríguez-Carlos… - Frontiers in …, 2023‏ - frontiersin.org
Mycobacterium tuberculosis (Mtb) is one of the most important infectious agents worldwide
and causes more than 1.5 million deaths annually. To make matters worse, the drug …

Emerging and future strategies in the management of recalcitrant Candida auris

N Bandara, L Samaranayake - Medical Mycology, 2022‏ - academic.oup.com
Candida auris is an emerging, multi drug resistant fungal pathogen that has caused
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …

[HTML][HTML] Discovery, optimization, and clinical application of natural antimicrobial peptides

AA Rodríguez, A Otero-González, M Ghattas… - Biomedicines, 2021‏ - mdpi.com
Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …

Pore-forming peptide C14R exhibits potent antifungal activity against clinical isolates of Candida albicans and Candida auris

N Vélez, A Argel, AK Kissmann… - Frontiers in cellular …, 2024‏ - frontiersin.org
Introduction Invasive candidiasis is a global public health problem as it poses a significant
threat in hospital-settings. The aim of this study was to evaluate C14R, an analog derived …

Promising Drug Candidates and New Strategies for Fighting against the Emerging Superbug Candida auris

M Billamboz, Z Fatima, S Hameed, S Jawhara - Microorganisms, 2021‏ - mdpi.com
Invasive fungal infections represent an expanding threat to public health. During the past
decade, a paradigm shift of candidiasis from Candida albicans to non-albicans Candida …

A systematical review on antimicrobial peptides and their food applications

K Xu, XY Zhao, Y Tan, J Wu, Y Cai, J Zhou… - Biomaterials Advances, 2023‏ - Elsevier
Food safety issues are a major concern in food processing and packaging industries. Food
spoilage is caused by microbial contamination, where antimicrobial peptides (APs) provide …