Frailty is an emerging global health burden, with major implications for clinical practice and
public health. The prevalence of frailty is expected to rise alongside rapid growth in the …

To estimate the risk of all‐cause mortality and hospitalization in frail patients with chronic
heart failure (HF), a systematic search and meta‐analysis was carried out to identify all …

Background: Frailty is increasing in prevalence. Because patients with frailty are often
perceived to have a less favorable risk/benefit profile, they may be less likely to receive new …

Background: Frailty may modify the risk− benefit profile of certain treatments, and frail
patients may have reduced tolerance to treatments. Objective: To investigate the efficacy of …

There is an increasing proportion of the general population surviving to old age with
significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state …

Heart failure (HF) and frailty are two distinct yet commonly associated conditions. The
interplay between the two conditions is complex, due to overlaps in underlying mechanisms …

Background Frailty is an increasingly common problem, and frail patients are less likely to
receive new pharmacologic therapies because the risk–benefit profile is perceived to be …

Abstract Background and Aims There is little information on the incremental prognostic
importance of frailty beyond conventional prognostic variables in heart failure (HF) …

summary Purpose The prevalence of frailty among patients with heart failure is about 45%.
Frailty may result in patients' functional decline, falls, disability, and decreased quality of life …

Frailty is a syndrome characterized by reduced physiological reserves, increased
vulnerability to stressors and adverse health outcomes. Frailty can change the prognosis …