Oncogenic mechanisms of COL10A1 in cancer and clinical challenges

Q Yi, G Zhu, W Zhu, J Wang, X Ouyang… - Oncology …, 2024 - spandidos-publications.com
Collagen type X α1 chain (COL10A1), a gene encoding the α-1 chain of type X collagen,
serves a key role in conferring tensile strength and structural integrity to tissues …

The role of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in cancer development and progression

CK Singh, S Fernandez, G Chhabra… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Collagen triple helix repeat containing 1 (CTHRC1) is a protein that has been
implicated in pro-migratory pathways, arterial tissue-repair processes, and inhibition of …

Evaluation of a Proteomics-Guided Protein Signature for Breast Cancer Detection in Breast Tissue

A Moreno-Ulloa, VL Zárate-Córdova… - Journal of Proteome …, 2024 - ACS Publications
The distinction between noncancerous and cancerous breast tissues is challenging in
clinical settings, and discovering new proteomics-based biomarkers remains underexplored …

Expression, Prognostic Value, and Biological Function of CTHRC1 in Different Types of Gliomas: A Bioinformatic Analysis and Experiment Validation

X Shi, X Zeng, R Jiao, Y Yang, X Du… - Clinical Medicine …, 2024 - journals.sagepub.com
Background: In recent years, abnormal expression of collagen triple helix repeat containing
1 (CTHRC1) has been found in some tumors, closely related to the poor prognosis of cancer …

FOXA1 is required for ErbB2 expression and luminal differentiation in HER2-positive breast cancer

J Jeong, J Lee, J Lim, J Shin, K Yoo, J Kim, Y Tanaka… - bioRxiv, 2024 - biorxiv.org
Forkhead box protein A1 (FOXA1), a pioneering transcriptional factor known for its critical
roles in prostate and ERα–positive breast cancer, is also expressed in human epidermal …

Transcriptome and methylome sequencing reveals altered long non-coding RNA genes expression and their aberrant DNA methylation in equine sarcoids

E Semik-Gurgul, A Gurgul, T Szmatoła - Functional & integrative genomics, 2023 - Springer
Recent publications confirmed that long non-coding RNAs (lncRNAs) perform an essential
function in gene-specific transcription regulation. Nevertheless, despite its important role …

Quantitative Proteomics of Breast Benign and Malignant Tumors Reveals a Malignancy Signature

A Moreno-Ulloa, VL Zárate-Córdova… - 2023 - researchsquare.com
The distinction between benign and malignant breast tumors is a challenge in clinical
settings. While omic studies have contributed to discovering genetic and proteomic …

[PDF][PDF] Aislamiento y caracterización de exosomas procedentes de líneas celulares: Identificación de nuevos biomarcadores para el cáncer de mama

RU Alonso, EC Arrastia - academica-e.unavarra.es
El cáncer de mama triple negativo (TNBC) es el subtipo más agresivo y con el pronóstico
más desfavorable. La tasa de supervivencia de las pacientes depende del estadio del tumor …