Nanoparticulate drug/gene carriers have gained much attention in the past decades
because of their versatile and tunable properties. However, efficacy of the therapeutic …

Abstract Design and synthesis of efficient drug delivery systems are of vital importance for
medicine and healthcare. Nanocarrier-based drug delivery systems, in particular …

Many diseases including cardiovascular disease, diabetes, osteoporosis, and cancers
cannot be treated effectively with current clinical therapy because of a significant reduction …

The development of biological methods over the past decade has stimulated great interest in
the possibility to regenerate human tissues. Advances in stem cell research, gene therapy …

Over the last 30 years, genetically engineered DNA has been tested as novel vaccination
strategy against various diseases, including human immunodeficiency virus (HIV), hepatitis …

Application of many vital hydrophilic medicines have been restricted by blood–brain barrier
(BBB) for treatment of brain diseases. In this study, a targeted drug delivery system based on …

For patients with hereditary retinal diseases, retinal gene therapy offers significant promise
for the prevention of retinal degeneration. While adeno-associated virus (AAV)-based …

Gene delivery is a promising technique that involves in vitro or in vivo introduction of
exogenous genes into cells for experimental and therapeutic purposes. Successful gene …

Biomedical Engineering An exploration of materials processing and engineering technology
across a wide range of medical applications The field of biomedical engineering has played …

One of the well-known X-linked genetic disorders is hemophilia, which could be hemophilia
A as a result of a mutation in the F8 (factor VIII) gene or hemophilia B as a result of a …