Xanthene, cyanine, oxazine and BODIPY: the four pillars of the fluorophore empire for super-resolution bioimaging

S Samanta, K Lai, F Wu, Y Liu, S Cai, X Yang… - Chemical Society …, 2023 - pubs.rsc.org
In the realm of biological research, the invention of super-resolution microscopy (SRM) has
enabled the visualization of ultrafine sub-cellular structures and their functions in live cells at …

Organic fluorescent probes for live-cell super-resolution imaging

X Duan, M Zhang, YH Zhang - Frontiers of Optoelectronics, 2023 - Springer
The development of super-resolution technology has made it possible to investigate the
ultrastructure of intracellular organelles by fluorescence microscopy, which has greatly …

Isotropic super-resolution light-sheet microscopy of dynamic intracellular structures at subsecond timescales

Y Zhao, M Zhang, W Zhang, Y Zhou, L Chen, Q Liu… - Nature …, 2022 - nature.com
Long-term visualization of the dynamic interactions between intracellular structures
throughout the three-dimensional space of whole live cells is essential to better understand …

Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells

H Fang, S Geng, M Hao, Q Chen, M Liu, C Liu… - Nature …, 2021 - nature.com
Zn2+ plays important roles in metabolism and signaling regulation. Subcellular Zn2+
compartmentalization is essential for organelle functions and cell biology, but there is …

Hydrophobicity is a key determinant in the activity of arginine-rich cell penetrating peptides

J Allen, JP Pellois - Scientific Reports, 2022 - nature.com
To deliver useful biological payloads into the cytosolic space of cells, cell-penetrating
peptides have to cross biological membranes. The molecular features that control or …

Green synthesis of highly fluorescent carbon quantum dots from almond resin for advanced theranostics in biomedical applications

PK Praseetha, RIJ Litany, HM Alharbi, AA Khojah… - Scientific Reports, 2024 - nature.com
Abstract Fluorescent Carbon Quantum Dots (CQDs) are being used in medical applications,
particularly in theranostics. These Carbon Quantum Dots have been gaining more attention …

Chemical analysis of single cells and organelles

K Hu, TDK Nguyen, S Rabasco, PE Oomen… - Analytical …, 2020 - ACS Publications
life science, clinical diagnostics, drug development, etc. Recent years have witnessed the
emergence of innovative analytical methods with high sensitivity and spatial-temporal …

Giant proteins in a giant cell: Molecular basis of ultrafast Ca2+-dependent cell contraction

J Zhang, W Qin, C Hu, S Gu, X Chai, M Yang… - Science …, 2023 - science.org
The giant single-celled eukaryote, Spirostomum, exhibits one of the fastest movements in
the biological world. This ultrafast contraction is dependent on Ca2+ rather than ATP and …

Surface-functionalized halo-tag gold nanoprobes for live-cell long-term super-resolution imaging of endoplasmic reticulum dynamics

P Xu, S Zhong, Y Wei, X Duan, M Zhang, W Shen… - ACS …, 2024 - ACS Publications
Super-resolution fluorescence microscopy has emerged as a powerful tool for studying
endoplasmic reticulum (ER) dynamics in living cells. However, the lack of high-brightness …

Elucidating the impact of payload conjugation on the cell-penetrating efficiency of the endosomal escape peptide dfTAT: implications for future designs for CPP-based …

J Diaz, M Pietsch, M Davila, G Jaimes… - Bioconjugate …, 2023 - ACS Publications
Cell-penetrating peptides (CPPs) are promising tools for the intracellular delivery of various
biological payloads. However, the impact of payload conjugation on the cell-penetrating …