[HTML][HTML] Advances in oral peptide drug nanoparticles for diabetes mellitus treatment
Y Li, W Zhang, R Zhao, X Zhang - Bioactive Materials, 2022 - Elsevier
Peptide drugs play an important role in diabetes mellitus treatment. Oral administration of
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines
Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …
absorption, low specificity, rapid degradation, and resistance development. The design and …
[HTML][HTML] Advances in nanomedicine for precision insulin delivery
Diabetes mellitus, which comprises a group of metabolic disorders affecting carbohydrate
metabolism, is characterized by improper glucose utilization and excessive production …
metabolism, is characterized by improper glucose utilization and excessive production …
Temozolomide-fatty acid conjugates for glioblastoma multiforme: In vitro and in vivo evaluation
Glioblastoma multiforme (GBM) is the deadliest brain tumor with a poor prognosis and
limited therapeutic options. Temozolomide (TMZ) is the first-line chemotherapeutic agent …
limited therapeutic options. Temozolomide (TMZ) is the first-line chemotherapeutic agent …
2, 2-Bis (hydroxymethyl) propionic acid based cyclic carbonate monomers and their (co) polymers as advanced materials for biomedical applications
Designing grafted biodegradable polymers with tailored multi-functional properties is one of
the most researched fields with extensive biomedical applications. Among many …
the most researched fields with extensive biomedical applications. Among many …
Self-assembly nanostructure of myristoylated ω-conotoxin MVIIA increases the duration of efficacy and reduces side effects
X Ding, Y Wang, S Zhang, R Zhang, D Chen, L Chen… - Marine Drugs, 2023 - mdpi.com
Chronic pain is one of the most prevalent health problems worldwide. An alternative to
suppress or alleviate chronic pain is the use of peptide drugs that block N-type Ca2+ …
suppress or alleviate chronic pain is the use of peptide drugs that block N-type Ca2+ …
Restoring physiological parameters of the pancreas and kidney through treatment with a polymeric nano-formulation of C-peptide and lisofylline combination in …
Diabetic nephropathy (DN) is a progressive kidney disorder that develops as a complication
of diabetes due to long-term exposure to elevated blood glucose levels (BGLs). In this case …
of diabetes due to long-term exposure to elevated blood glucose levels (BGLs). In this case …
An apprise on novel drug delivery systems for management of diabetes mellitus
In the context of therapeutics for Type 2 Diabetes Mellitus, challenges emerge when
conventional strategies, including diet and exercise, fall short of adequately controlling …
conventional strategies, including diet and exercise, fall short of adequately controlling …
[HTML][HTML] Self-emulsifying micelles as a drug nanocarrier system for itraconazole oral bioavailability enhancement; in vitro and in vivo assessment
Itraconazole (ITZ) is a renowned antifungal medication, however its therapeutic efficacy is
limited by low solubility and oral bioavailability. The current research work attempted to …
limited by low solubility and oral bioavailability. The current research work attempted to …
Nanoparticulate tablet dosage form of lisofylline-linoleic acid conjugate for type 1 diabetes: in situ single-pass intestinal perfusion (SPIP) studies and …
Lisofylline (LSF) is an anti-inflammatory molecule with high aqueous solubility and rapid
metabolic interconversion to its parent drug, pentoxifylline (PTX) resulting in very poor …
metabolic interconversion to its parent drug, pentoxifylline (PTX) resulting in very poor …