Candida albicans cell-type switching and functional plasticity in the mammalian host

SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …

Genetic control of Candida albicans biofilm development

JS Finkel, AP Mitchell - Nature Reviews Microbiology, 2011 - nature.com
Candida species cause frequent infections owing to their ability to form biofilms—surface-
associated microbial communities—primarily on implanted medical devices. Increasingly …

The first isolate of Candida auris in China: clinical and biological aspects

X Wang, J Bing, Q Zheng, F Zhang, J Liu… - Emerging microbes & …, 2018 - Taylor & Francis
The emerging human fungal pathogen Candida auris has been recognized as a multidrug
resistant species and is associated with high mortality. This fungus was first described in …

Candida albicans hyphal initiation and elongation

Y Lu, C Su, H Liu - Trends in microbiology, 2014 - cell.com
The fungus Candida albicans is a benign member of the mucosal microbiota, but can cause
mucosal infections and life-threatening disseminated invasive infections in susceptible …

Adapting to survive: How Candida overcomes host-imposed constraints during human colonization

R Alves, C Barata-Antunes, M Casal, AJP Brown… - PLoS …, 2020 - journals.plos.org
Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

N‐acetylglucosamine functions in cell signaling

JB Konopka - Scientifica, 2012 - Wiley Online Library
The amino sugar N‐acetylglucosamine (GlcNAc) is well known for the important structural
roles that it plays at the cell surface. It is a key component of bacterial cell wall …

Discovery of a “White-Gray-Opaque” Tristable Phenotypic Switching System in Candida albicans: Roles of Non-genetic Diversity in Host Adaptation

L Tao, H Du, G Guan, Y Dai, CJ Nobile, W Liang… - PLoS …, 2014 - journals.plos.org
Non-genetic phenotypic variations play a critical role in the adaption to environmental
changes in microbial organisms. Candida albicans, a major human fungal pathogen, can …

Regulation of phenotypic transitions in the fungal pathogen Candida albicans

G Huang - Virulence, 2012 - Taylor & Francis
The human commensal fungus Candida albicans can cause not only superficial infections,
but also life-threatening disease in immunocompromised individuals. C. albicans can grow …

Candida and candidiasis in HIV-infected patients: where commensalism, opportunistic behavior and frank pathogenicity lose their borders

A Cassone, R Cauda - Aids, 2012 - journals.lww.com
In this era of efficacious antiretroviral therapy and consequent immune reconstitution,
oropharyngeal and esophageal candidiasis (OPC and OEC) still remain two clinically …

Sugar Sensing and Signaling in Candida albicans and Candida glabrata

M Van Ende, S Wijnants, P Van Dijck - Frontiers in microbiology, 2019 - frontiersin.org
Candida species, such as Candida albicans and Candida glabrata, cause infections at
different host sites because they adapt their metabolism depending on the available …