Cortisol, a critical glucocorticoid hormone produced by the adrenal glands, plays a pivotal
role in various physiological processes. Its release is finely orchestrated by the …

A plethora of research has implicated hundreds of putative biomarkers for depression, but
has not yet fully elucidated their roles in depressive illness or established what is abnormal …

Objective Research on HPA axis dysregulation has been associated with vulnerability to, or
perseverence of, several mental disorders. Hoever, measurements of cortisol levels in …

Objectives This review systematically examined the associations between chronic stress
and hair cortisol concentration (HCC) in children, and the potential modification effects of …

Today, routine do** controls largely rely on testing whole blood, serum, and urine
samples. These matrices allow comprehensively covering inorganic as well as low and high …

Abstract Major Depressive Disorder (MDD) or depression is a pathological mental condition
affecting millions of people worldwide. Identification of objective biological markers of …

Literature supports a causal role of stress in major depressive disorder (MDD). Hair cortisol
concentration (HCC) has been widely used as a measure of long-term stress. Although …

Cortisol, a crucial steroid hormone synthesized by the adrenal glands, has diverse impacts
on multiple physiological processes, such as metabolism, immune function, and stress …

Much of the existing research on biological mechanisms underlying the stress experience
has focused largely on moment‐to‐moment stress, rather than on chronic stress, an …

Quantitating glucocorticoids (GCs) in hairs is a popular method for assessing chronic stress
in studies of humans and animals alike. The cause-and-effect relationship between stress …