The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …

Eosinophils are a class of granulocytes with pleiotropic functions in homeostasis and
various human diseases. Nevertheless, they are absent from conventional single-cell RNA …

Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a vasculitis
characterized by eosinophilic inflammation. Benralizumab, a monoclonal antibody against …

Eosinophils are bone marrow-derived granulocytes that, under homeostatic conditions,
account for as much as 1-3% of peripheral blood leukocytes. During inflammation …

The unified airway hypothesis proposes that upper and lower airway diseases reflect a
single pathological process manifesting in different locations within the airway. Functional …

Eosinophils play a key role in airway inflammation in many diseases, such as allergic and
non-allergic asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive …

Since its global invasion in 2019, COVID-19 has affected several aspects of patients' lives
and posed a significant impact on the health care system. Several patient populations were …

Gender differences in the functionality of the immune system have been attributed, in part, to
direct and indirect effects of sex steroids, especially estrogens, on immune cell repertoire …

Background In mice models, eosinophils have been divided into different subpopulations
with distinct phenotypes and functions, based on CD62L and CD101 patterns of membrane …

Rationale: There is a differential response to eosinophilic modulation between patients with
asthma and those with chronic obstructive pulmonary disease (COPD). There is also …