Despite considerable recent progress in defining neutrophil functions and behaviors in
tissue repair, much remains to be determined with regards to its overall role in the tissue …

Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

Significance: Neutrophils are one of the most abundant cells of the immune system and they
are extremely active during the repair of cutaneous wounds. In general, the antimicrobial …

The stroma in solid tumors contains a variety of cellular phenotypes and signaling pathways
associated with wound healing, leading to the concept that a tumor behaves as a wound that …

Significance: Proteases and their inhibitors contribute to the balance between extracellular
matrix (ECM) degradation and deposition, creating an equilibrium that is essential for the …

Antimicrobial peptides (AMPs) are widely expressed and rapidly induced at epithelial
surfaces to repel assault from diverse infectious agents including bacteria, viruses, fungi and …

Cathelicidins comprise a family of mammalian proteins containing a C-terminal cationic
antimicrobial domain that becomes active after being freed from the N-terminal cathelin …

Cationic antimicrobial peptides are produced by all organisms, from plants and insects to
human beings, as a major part of their immediately effective, nonspecific defences against …

Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative
granules of neutrophils. The known biologic functions reside in the C-terminus, which must …

In mammals, several gene families encode peptides with antibacterial activity, such as the β-
defensins and cathelicidins,,. These peptides are expressed on epithelial surfaces and in …