The anterior cingulate cortex (ACC) is implicated in a broad range of behaviors and
cognitive processes, but it has been unclear what contribution, if any, the ACC makes to …

Social cognition is a complex process that requires the integration of a wide variety of
behaviors, including salience, reward-seeking, motivation, knowledge of self and others …

Studies of humans with focal brain damage and non-human animals with experimentally
induced brain lesions have provided pivotal insights into the neural basis of behavior. As the …

The orbitofrontal cortex (OFC) has long been associated with the flexible control of behavior
and concepts such as behavioral inhibition, self-control, and emotional regulation. These …

Reward-guided decision-making depends on a network of brain regions. Among these are
the orbitofrontal and the anterior cingulate cortex. However, it is difficult to ascertain if these …

Emerging evidence has shown that social pain—the painful feelings that follow from social
rejection, exclusion, or loss—relies on some of the same neural regions that process …

Recent work has emphasized the role that orbitofrontal cortex (OFC) has in value-based
decision-making. However, it is also clear that a number of discrepancies have arisen when …

Background Connectivity between the amygdala and ventromedial prefrontal cortex
(vmPFC) is compromised in multiple psychiatric disorders, many of which emerge during …

Choices are often intertemporal, requiring tradeoff of short-term and long-term outcomes. In
such contexts, humans may prefer small rewards delivered immediately to larger rewards …

Clinical depression can occur in young children as early as age three. This very early onset
variant of depression shows the same clinical features with developmental adjustments as …