Anticancer drugs repurposed for Alzheimer's disease: A systematic review

A Ancidoni, I Bacigalupo, G Remoli, E Lacorte… - Alzheimer's Research & …, 2021 - Springer
Background The relationship between cancer and dementia is triggering growing research
interest. Several preclinical studies have provided the biological rationale for the …

The APOE ε4 variant and hippocampal atrophy in Alzheimer's disease and Lewy body dementia: a systematic review of magnetic resonance imaging studies and …

U Saeed, P Desmarais, M Masellis - Expert Review of …, 2021 - Taylor & Francis
Introduction: The apolipoprotein E ɛ4-allele (APOE-ɛ4) increases the risk not only for
Alzheimer's disease (AD) but also for Parkinson's disease dementia and dementia with …

Bexarotene attenuates early brain injury via inhibiting micoglia activation through PPARγ after experimental subarachnoid hemorrhage

L Tu, X Yang, Q Zhang, Q Wang, T Tian… - Neurological …, 2018 - Taylor & Francis
Objectives Early brain injury (EBI) is considered to be one of the main causes of poor
outcome in subarachnoid hemorrhage (SAH) patients. Bexarotene is an agonist of retinoid X …

Foresee novel targets for Alzheimer's disease by investigating repurposed drugs

K Agarwal, DP Katare… - CNS & Neurological …, 2023 - benthamdirect.com
Background: Alzheimer's Disease (AD) is the most rampant neurodegenerative disorder
which has caused havoc worldwide. More than a century has passed since the first case of …