Wall shear stress and its role in atherosclerosis
M Zhou, Y Yu, R Chen, X Liu, Y Hu, Z Ma… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …
morbidity and mortality in countries around the world. Atherosclerosis combines the …
[HTML][HTML] Animal models of atherosclerosis
An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology
and has the potential to be used in medical and pharmaceutical research to obtain results …
and has the potential to be used in medical and pharmaceutical research to obtain results …
Multicentre, randomized comparison of two-stent and provisional stenting techniques in patients with complex coronary bifurcation lesions: the DEFINITION II trial
JJ Zhang, F Ye, K Xu, J Kan, L Tao… - European Heart …, 2020 - academic.oup.com
Aim The present study aimed to assess the benefits of two-stent techniques for patients with
DEFINITION criteria-defined complex coronary bifurcation lesions. Methods and results In …
DEFINITION criteria-defined complex coronary bifurcation lesions. Methods and results In …
Effects of shear stress on endothelial cells: go with the flow
Haemodynamic forces influence the functional properties of vascular endothelium.
Endothelial cells (ECs) have a variety of receptors, which sense flow and transmit …
Endothelial cells (ECs) have a variety of receptors, which sense flow and transmit …
Molecular biology of atherosclerosis
PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
Shear-dependent platelet aggregation: mechanisms and therapeutic opportunities
A Rana, E Westein, B Niego… - Frontiers in cardiovascular …, 2019 - frontiersin.org
Cardiovascular diseases (CVD) are the number one cause of morbidity and death
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …
worldwide. As estimated by the WHO, the global death rate from CVD is 31% wherein, a …
Pathology of the vulnerable plaque
R Virmani, AP Burke, A Farb, FD Kolodgie - Journal of the American …, 2006 - jacc.org
The majority of patients with acute coronary syndromes (ACS) present with unstable angina,
acute myocardial infarction, and sudden coronary death. The most common cause of …
acute myocardial infarction, and sudden coronary death. The most common cause of …
Comprehensive plaque assessment by coronary CT angiography
Most acute coronary syndromes are caused by sudden luminal thrombosis due to
atherosclerotic plaque rupture or erosion. Preventing such an event seems to be the only …
atherosclerotic plaque rupture or erosion. Preventing such an event seems to be the only …
Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis
P Deb, S Sharma, KM Hassan - Pathophysiology, 2010 - Elsevier
Stroke is a serious neurological disease, and constitutes a major cause of death and
disability throughout the world. The pathophysiology of stroke is complex, and involves …
disability throughout the world. The pathophysiology of stroke is complex, and involves …
Endothelial shear stress in the evolution of coronary atherosclerotic plaque and vascular remodelling: current understanding and remaining questions
JJ Wentzel, YS Chatzizisis, FJH Gijsen… - Cardiovascular …, 2012 - academic.oup.com
The heterogeneity of plaque formation, the vascular remodelling response to plaque
formation, and the consequent phenotype of plaque instability attest to the extraordinarily …
formation, and the consequent phenotype of plaque instability attest to the extraordinarily …