Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus

MD Johansen, JL Herrmann, L Kremer - Nature Reviews Microbiology, 2020 - nature.com
Infections caused by non-tuberculous mycobacteria (NTM) are increasing globally and are
notoriously difficult to treat due to intrinsic resistance of these bacteria to many common …

Immune Response to Mycobacterium tuberculosis: A Narrative Review

M De Martino, L Lodi, L Galli, E Chiappini - Frontiers in pediatrics, 2019 - frontiersin.org
The encounter between Mycobacterium tuberculosis (Mtb) and the host leads to a complex
and multifaceted immune response possibly resulting in latent infection, tubercular disease …

The immunoregulatory landscape of human tuberculosis granulomas

EF McCaffrey, M Donato, L Keren, Z Chen… - Nature …, 2022 - nature.com
Tuberculosis (TB) in humans is characterized by formation of immune-rich granulomas in
infected tissues, the architecture and composition of which are thought to affect disease …

Macrophage: a cell with many faces and functions in tuberculosis

F Ahmad, A Rani, A Alam, S Zarin, S Pandey… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …

Immunology of Mycobacterium tuberculosis Infections

JK Sia, J Rengarajan - Microbiology spectrum, 2019 - journals.asm.org
Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

[HTML][HTML] Tuberculosis and lung damage: from epidemiology to pathophysiology

S Ravimohan, H Kornfeld… - European respiratory …, 2018 - publications.ersnet.org
A past history of pulmonary tuberculosis (TB) is a risk factor for long-term respiratory
impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high …

Heterogeneity in tuberculosis

AM Cadena, SM Fortune, JAL Flynn - Nature Reviews Immunology, 2017 - nature.com
Infection with Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), results
in a range of clinical presentations in humans. Most infections manifest as a clinically …

New insights into the evasion of host innate immunity by Mycobacterium tuberculosis

Q Chai, L Wang, CH Liu, B Ge - Cellular & molecular immunology, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …

The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress

K Dua, R Wadhwa, G Singhvi, V Rapalli… - Drug development …, 2019 - Wiley Online Library
Lung diseases are the leading cause of mortality worldwide. The currently available
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …

Clinical manifestations and immune response to tuberculosis

ML Carabalí-Isajar, OH Rodríguez-Bejarano… - World Journal of …, 2023 - Springer
Tuberculosis is a far-reaching, high-impact disease. It is among the top ten causes of death
worldwide caused by a single infectious agent; 1.6 million tuberculosis-related deaths were …