Molecularly imprinted polymer nanoparticles: an emerging versatile platform for cancer therapy

S Xu, L Wang, Z Liu - Angewandte Chemie International …, 2021 - Wiley Online Library
Molecularly imprinted polymers (MIPs) are chemically synthesized affinity materials with
tailor‐made binding cavities complementary to the template molecules in shape, size, and …

Nucleic acid-based molecular computation heads towards cellular applications

L Chen, W Chen, G Liu, J Li, C Lu, J Li, W Tan… - Chemical Society …, 2021 - pubs.rsc.org
Nucleic acids, with the advantages of programmability and biocompatibility, have been
widely used to design different kinds of novel biocomputing devices. Recently, nucleic acid …

A smart, autocatalytic, DNAzyme biocircuit for in vivo, amplified, microRNA imaging

J Wei, H Wang, Q Wu, X Gong, K Ma, X Liu… - Angewandte …, 2020 - Wiley Online Library
DNAzymes have been recognized as promising transducing agents for visualizing
endogenous biomarkers, but their inefficient intracellular delivery and limited amplification …

Simultaneous visualization of dual intercellular signal transductions via SERS imaging of membrane proteins dimerization on single cells

C Dong, X Fang, J **ong, J Zhang, H Gan, C Song… - ACS …, 2022 - ACS Publications
The visualization of protein dimerization on live cells is an urgent need and of vital
importance for facile monitoring the signal transduction during intercellular communication …

Aptamer-functionalized DNA origami for targeted codelivery of antisense oligonucleotides and doxorubicin to enhance therapy in drug-resistant cancer cells

Q Pan, C Nie, Y Hu, J Yi, C Liu, J Zhang… - … applied materials & …, 2019 - ACS Publications
Drug resistance is a major obstacle to the efficient therapy of drug-resistant cancer. To
overcome this problem, we constructed a multifunctional DNA origami-based nanocarrier for …

Core–shell structured magnetic covalent organic framework nanocomposites for triclosan and triclocarban adsorption

Y Li, H Zhang, Y Chen, L Huang, Z Lin… - ACS applied materials & …, 2019 - ACS Publications
Triclosan (TCS) and triclocarban (TCC) are widely used as bactericides in personal-care
products. They are frequently found in environmental water and have the potential to cause …

Engineering receptor-mediated transmembrane signaling in artificial and living cells

K Shi, C Song, Y Wang, R Chandrawati… - Communications …, 2023 - nature.com
Living cells possess a variety of transmembrane signaling systems that receive chemical
and physical cues from the environment and transduce this information into an intracellular …

Biointerface engineering with nucleic acid materials for biosensing applications

S Shi, J Chen, X Wang, M **ao… - Advanced Functional …, 2022 - Wiley Online Library
Molecular recognition at the biointerface plays a critical role in sensing molecular
interactions (eg, DNA hybridization) and extracellular changes, which can directly affect the …

Neoantigen-targeted TCR-engineered T cell immunotherapy: current advances and challenges

Z Pang, M Lu, Y Zhang, Y Gao, J Bai, J Gu, L **e… - Biomarker …, 2023 - Springer
Adoptive cell therapy using T cell receptor-engineered T cells (TCR-T) is a promising
approach for cancer therapy with an expectation of no significant side effects. In the human …

Spatially reprogramed receptor organization to switch cell behavior using a DNA origami-templated aptamer nanoarray

M Wang, D Yang, Q Lu, L Liu, Z Cai, Y Wang… - Nano Letters, 2022 - ACS Publications
Receptor oligomerization is a highly complex molecular process that modulates divergent
cell signaling. However, there is a lack of molecular tools for systematically interrogating …