Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics

R Tenchov, JM Sasso, X Wang, WS Liaw, CA Chen… - ACS …, 2022 - ACS Publications
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Exosome-based smart drug delivery tool for cancer theranostics

R Kar, R Dhar, S Mukherjee, S Nag… - ACS biomaterials …, 2023 - ACS Publications
Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles
derived from the plasma membrane. The main activity of exosomes is cellular …

Acoustofluidics for biomedical applications

J Rufo, F Cai, J Friend, M Wiklund… - Nature Reviews Methods …, 2022 - nature.com
Acoustofluidic technologies utilize acoustic waves to manipulate fluids and particles within
fluids, all in a contact-free and biocompatible manner. Over the past decade, acoustofluidic …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: applications in regenerative medicine

MD Hade, CN Suire, Z Suo - Cells, 2021 - mdpi.com
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Detection of neuron-derived pathological α-synuclein in blood

A Kluge, J Bunk, E Schaeffer, A Drobny, W **ang… - Brain, 2022 - academic.oup.com
To date, no reliable clinically applicable biomarker has been established for Parkinson's
disease. Our results indicate that a long anticipated blood test for Parkinson's disease may …

A role for microfluidic systems in precision medicine

JM Ayuso, M Virumbrales-Muñoz, JM Lang… - Nature …, 2022 - nature.com
Precision oncology continues to challenge the “one-size-fits-all” dogma. Under the precision
oncology banner, cancer patients are screened for molecular tumor alterations that predict …

The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities

CM Neophytou, M Panagi, T Stylianopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Metastasis, the process by which cancer cells escape primary tumor site
and colonize distant organs, is responsible for most cancer-related deaths. The tumor …

Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders

A Markov, L Thangavelu, S Aravindhan… - Stem cell research & …, 2021 - Springer
Over recent years, mesenchymal stem/stromal cells (MSCs) and their potential biomedical
applications have received much attention from the global scientific community in an …

Innovative approaches for cancer treatment: Current perspectives and new challenges

C Pucci, C Martinelli, G Ciofani - ecancermedicalscience, 2019 - pmc.ncbi.nlm.nih.gov
Every year, cancer is responsible for millions of deaths worldwide and, even though much
progress has been achieved in medicine, there are still many issues that must be addressed …

Exosomes from adipose‐derived stem cells and application to skin wound healing

Y An, S Lin, X Tan, S Zhu, F Nie, Y Zhen, L Gu… - Cell …, 2021 - Wiley Online Library
Skin wound healing is an intractable problem that represents an urgent clinical need. To
solve this problem, a large number of studies have focused on the use of exosomes (EXOs) …