The retinal pigment epithelium (RPE), a monolayer of post-mitotic polarized epithelial cells,
strategically situated between the photoreceptors and the choroid, is the primary caretaker of …

Mesenchymal stem cells (MSCs) are the most frequently used stem cells in clinical trials due
to their easy isolation from various adult tissues, their ability of homing to injury sites and …

Abstract Extracellular vesicles (EVs) are 30–150 nm membrane-bound vesicles naturally
secreted by cells and play important roles in intercellular communication by delivering …

Age‐related macular degeneration (AMD) is a leading cause of blindness worldwide.
Drusen are key contributors to the etiology of AMD and the ability to modulate drusen …

Albinism is a pigment disorder affecting eye, skin and/or hair. Patients usually have
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …

Renal ischemia/reperfusion (I/R) injury is the main reason for acute kidney injury (AKI) and is
closely related to high morbidity and mortality. In this study, we found that exosomes from …

We speculate that exosomes derived from human umbilical cord mesenchymal stromal cells
(HUC-MSCs) will accumulate within tumors and have the potential for both tumor location or …

Mesenchymal stem cell (MSCs)-derived extracellular vesicles (EVs) are emerging
therapeutic tools. Hypoxic pre-conditioning (HPC) of MSCs altered the production of …

CRISPR/Cas9 genome editing is a very promising avenue for the treatment of a variety of
genetic diseases. However, it is still very challenging to encapsulate CRISPR/Cas9 …

Exosomes, nanoscale vesicles with a diameter of 30 to 150 nm, are composed of a lipid
bilayer, protein, and genetic material. Exosomes are secreted by virtually all types of cells in …