MicroRNA biogenesis pathways in cancer

S Lin, RI Gregory - Nature reviews cancer, 2015 - nature.com
MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and
overexpression of individual'oncomiRs' or genetic loss of tumour suppressor miRNAs are …

Micro-RNA: The darkhorse of cancer

M Budakoti, AS Panwar, D Molpa, RK Singh… - Cellular signalling, 2021 - Elsevier
The discovery of micro RNAs (miRNA) in cancer has opened up new vistas for researchers
in recent years. Micro RNAs area set of small, endogenous, highly conserved, non-coding …

The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer

ML Tornesello, R Faraonio, L Buonaguro… - Frontiers in …, 2020 - frontiersin.org
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …

[HTML][HTML] MicroRNA and cancer

MD Jansson, AH Lund - Molecular oncology, 2012 - Elsevier
With the advent of next generation sequencing techniques a previously unknown world of
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …

DICER1: mutations, microRNAs and mechanisms

WD Foulkes, JR Priest, TF Duchaine - Nature Reviews Cancer, 2014 - nature.com
Dicer is central to microRNA-mediated silencing and several other RNA interference
phenomena that are profoundly embedded in cancer gene networks. Most recently, both …

Driver and passenger mutations in cancer

JR Pon, MA Marra - Annual Review of Pathology: Mechanisms …, 2015 - annualreviews.org
Next-generation sequencing has allowed identification of millions of somatic mutations and
epigenetic changes in cancer cells. A key challenge in interpreting cancer genomes and …

MicroRNAs in cancer

YS Lee, A Dutta - Annual Review of Pathology: Mechanisms of …, 2009 - annualreviews.org
Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the
scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent …

MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype

C Blenkiron, LD Goldstein, NP Thorne, I Spiteri… - Genome biology, 2007 - Springer
Background MicroRNAs (miRNAs), a class of short non-coding RNAs found in many plants
and animals, often act post-transcriptionally to inhibit gene expression. Results Here we …

Dysregulation of microRNA biogenesis machinery in cancer

A Hata, R Kashima - Critical reviews in biochemistry and molecular …, 2016 - Taylor & Francis
MicroRNAs (miRNAs) are integral to the gene regulatory network. A single miRNA is
capable of controlling the expression of hundreds of protein coding genes and modulate a …

Mechanisms of control of microRNA biogenesis

BN Davis-Dusenbery, A Hata - The journal of biochemistry, 2010 - academic.oup.com
MicroRNAs (miRNAs) are a class of∼ 22 nt non-coding RNAs that control diverse biological
functions in animals, plants and unicellular eukaryotes by promoting degradation or …