C-Glycopyranosyl Arenes and Hetarenes: Synthetic Methods and Bioactivity Focused on Antidiabetic Potential

E Bokor, S Kun, D Goyard, M Toth, JP Praly… - Chemical …, 2017 - ACS Publications
This Review summarizes close to 500 primary publications and surveys published since
2000 about the syntheses and diverse bioactivities of C-glycopyranosyl (het) arenes. A …

Glycosyltransferases: mechanisms and applications in natural product development

DM Liang, JH Liu, H Wu, BB Wang, HJ Zhu… - Chemical Society …, 2015 - pubs.rsc.org
Glycosylation reactions mainly catalyzed by glycosyltransferases (Gts) occur almost
everywhere in the biosphere, and always play crucial roles in vital processes. In order to …

Leloir glycosyltransferases as biocatalysts for chemical production

B Nidetzky, A Gutmann, C Zhong - ACS Catalysis, 2018 - ACS Publications
Glycosylation is a chemical transformation that is centrally important in all glycoscience and
related technologies. Catalysts offering good control over reactivity and selectivity in …

Sucrose synthase: A unique glycosyltransferase for biocatalytic glycosylation process development

K Schmölzer, A Gutmann, M Diricks, T Desmet… - Biotechnology …, 2016 - Elsevier
Abstract Sucrose synthase (SuSy, EC 2.4. 1.13) is a glycosyltransferase (GT) long known
from plants and more recently discovered in bacteria. The enzyme catalyzes the reversible …

Biotechnological advances in UDP-sugar based glycosylation of small molecules

F De Bruyn, J Maertens, J Beauprez, W Soetaert… - Biotechnology …, 2015 - Elsevier
Glycosylation of small molecules like specialized (secondary) metabolites has a profound
impact on their solubility, stability or bioactivity, making glycosides attractive compounds as …

Leloir glycosyltransferases in applied biocatalysis: A multidisciplinary approach

L Mestrom, M Przypis, D Kowalczykiewicz… - International Journal of …, 2019 - mdpi.com
Enzymes are nature's catalyst of choice for the highly selective and efficient coupling of
carbohydrates. Enzymatic sugar coupling is a competitive technology for industrial …

Probing the Catalytic Promiscuity of a Regio‐ and Stereospecific C‐Glycosyltransferase from Mangifera indica

D Chen, R Chen, R Wang, J Li, K **e… - Angewandte …, 2015 - Wiley Online Library
The catalytic promiscuity of the novel benzophenone C‐glycosyltransferase, MiCGT, which
is involved in the biosynthesis of mangiferin from Mangifera indica, was explored. MiCGT …

Reprint of: Advanced glycosidases as ingenious biosynthetic instruments

Z Mészáros, P Nekvasilová, P Bojarová, V Křen… - Biotechnology …, 2021 - Elsevier
Until recently, glycosidases, naturally hydrolyzing carbohydrate-active enzymes, have found
few synthetic applications in industry, being primarily used for cleaving unwanted …

Recent progress on feasible strategies for arbutin production

KX Xu, MG Xue, Z Li, BC Ye, B Zhang - Frontiers in Bioengineering …, 2022 - frontiersin.org
Arbutin is a hydroquinone glucoside and a natural product present in various plants. Arbutin
potently inhibits melanin formation. This property has been exploited in whitening cosmetics …

Advances on the in vivo and in vitro glycosylations of flavonoids

Y Ji, B Li, M Qiao, J Li, H Xu, L Zhang… - Applied Microbiology and …, 2020 - Springer
Flavonoids possess diverse bioactivity and potential medicinal values. Glycosylation of
flavonoids, coupling flavonoid aglycones and glycosyl groups in conjugated form, can …