Prevention, treatment and cure of HIV infection

RJ Landovitz, H Scott, SG Deeks - Nature Reviews Microbiology, 2023‏ - nature.com
The development of antiretroviral therapy for the prevention and treatment of HIV infection
has been marked by a series of remarkable successes. However, the efforts to develop a …

Integrated care models: HIV and substance use

K Hill, I Kuo, SV Shenoi, MS Desruisseaux… - Current HIV/AIDS …, 2023‏ - Springer
Abstract Purpose of Review Behaviors and practices associated with substance use
contribute to lack of HIV virologic suppression and onward transmission. In the USA, many …

Virological failure after switch to long-acting cabotegravir and rilpivirine injectable therapy: an in-depth analysis

BJ van Welzen, SFL Van Lelyveld… - Clinical Infectious …, 2024‏ - academic.oup.com
Background Long-acting (LA) injectable therapy with cabotegravir (CAB) and rilpivirine
(RPV) is currently used as maintenance treatment for human immunodeficiency virus type 1 …

Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections

FYS Kong, C Kenyon, M Unemo - Journal of Antimicrobial …, 2023‏ - academic.oup.com
Rates of sexually transmitted infections (STIs) continue to rise across the world and
interventions are essential to reduce their incidence. Past and recent studies have indicated …

Mpox and HIV: a narrative review

CS Saldana, CF Kelley, BM Aldred… - Current HIV/AIDS Reports, 2023‏ - Springer
Abstract Purpose of Review We reviewed the available literature on mpox in People with
HIV (PWH). We highlight special considerations of mpox infection related to epidemiology …

Prevention strategies for sexually transmitted infections, HIV, and viral hepatitis in Europe

D Gökengin, T Noori, A Alemany… - The Lancet Regional …, 2023‏ - thelancet.com
The current prevention efforts for STIs, HIV and viral hepatitis in the WHO European Region,
especially in the Central and Eastern subregions, are hindered by healthcare disparities …

Profiling the interaction between human serum albumin and clinically relevant HIV reverse transcriptase inhibitors

A Costa-Tuna, OA Chaves, ZL Almeida, RS Cunha… - Viruses, 2024‏ - mdpi.com
Tenofovir (TFV) is the active form of the prodrugs tenofovir disoproxil fumarate (TDF) and
tenofovir alafenamide (TAF), both clinically prescribed as HIV reverse transcriptase …

Impact of integrase inhibitors on cardiovascular disease events in people with human immunodeficiency virus starting antiretroviral therapy

B Surial, F Chammartin, J Damas… - Clinical Infectious …, 2023‏ - academic.oup.com
Background Integrase strand transfer inhibitors (INSTIs) have been associated with an
increased risk for cardiovascular disease (CVD) events. We investigated the impact of …

In vivo HIV dynamics, modeling the interaction of HIV and immune system via non-integer derivatives

A Jan, HM Srivastava, A Khan, PO Mohammed… - Fractal and …, 2023‏ - mdpi.com
The economic burden of HIV extends beyond the individual level and affects communities
and countries. HIV can lead to decreased economic growth due to lost productivity and …

Epistatic pathways can drive HIV-1 escape from integrase strand transfer inhibitors

Y Hikichi, JR Grover, A Schäfer, W Mothes… - Science …, 2024‏ - science.org
People living with human immunodeficiency virus (HIV) receiving integrase strand transfer
inhibitors (INSTIs) have been reported to experience virological failure in the absence of …