Simple Summary The relationship between the immune system and tumours is currently one
of the most studied topics in the field of cancer. Previously, it was thought that a tumour could …

B Lymphocytes and Cancer: A Love–Hate Relationship: Trends in Cancer Skip to Main Content
Skip to Main Menu Advertisement Trends in Cancer This journal offers authors two options …

Chemokines have crucial roles in organ development and orchestration of leukocyte
migration. The chemokine CCL22 is expressed constitutively at high levels in the lymph …

We have identified a novel gene referred to asactivation-induced deaminase (AID) by
subtraction of cDNAs derived from switch-induced and uninduced murine B lymphoma …

Tumor-infiltrating CD8+ T cells are strongly associated with patient survival in a wide variety
of human cancers. Less is known about tumor-infiltrating CD20+ B cells, which often …

As few as one in 100,000 B and T lymphocytes are specific for a single protein antigen, such
as tetanus toxin, yet these cells must come together if an antibody response is to occur …

The immune system is composed of single cells, and its function is entirely dependent on the
capacity of these cells to traffic, localize within tissues, and interact with each other in a …

Migration of antigen-activated CD4 T cells to B cell areas of lymphoid tissues is important for
mounting T cell–dependent antibody responses. Here we show that CXC chemokine …

Dendritic cells (DC) have been showed to both produce and respond to chemokines. To
understand how this may impact on DC function, we analyzed the kinetics of chemokine …

The maternal immune system plays a critical role in the establishment, maintenance, and
completion of a healthy pregnancy. However, the specific mechanisms utilized to achieve …