Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review

G Petrisor, L Motelica, LN Craciun, OC Oprea… - International Journal of …, 2022 - mdpi.com
Melissa officinalis is a medicinal plant rich in biologically active compounds which is used
worldwide for its therapeutic effects. Chemical studies on its composition have shown that it …

Metabolomics technologies for the identification and quantification of dietary phenolic compound metabolites: an overview

A López-Yerena, I Domínguez-López… - Antioxidants, 2021 - mdpi.com
In the search for natural products with properties that may protect against or slow down
chronic and degenerative diseases (eg, cancer, and cardiovascular and neurodegenerative …

[HTML][HTML] Appraisal of a new potential antioxidants-rich nutraceutical ingredient from chestnut shells through in-vivo assays–A targeted metabolomic approach in …

D Pinto, A Almeida, A López-Yerena, S Pinto… - Food Chemistry, 2023 - Elsevier
Chestnut (Castanea sativa) shells (CSS) are a source of bioactive compounds with well
demonstrated in-vitro antioxidant properties. Nevertheless, no in-vivo studies have already …

Dragon fruits as a reservoir of natural polyphenolics with chemopreventive properties

P Paśko, A Galanty, P Zagrodzki, P Luksirikul… - Molecules, 2021 - mdpi.com
Dragon fruits are a valued source of bioactive compounds with high potential to become a
functional food. The aim of the study was to evaluate and compare the chemopreventive …

Using human serum albumin binding affinities as a proactive strategy to affect the pharmacodynamics and pharmacokinetics of preclinical drug candidates

J Fan, K Gilmartin, S Octaviano, F Villar… - ACS Pharmacology & …, 2022 - ACS Publications
We report on a new preclinical drug optimization strategy that measures drug candidates'
binding affinity with human serum albumin (HSA) as an assessment of increasing or …

Brazilian passion fruit as a new healthy food: from its composition to health properties and mechanisms of action

IAE Duarte, D Milenkovic, TK Borges, LL de Oliveira… - Food & Function, 2021 - pubs.rsc.org
The Brazilian biodiversity is one of the largest in the world, with about 41 000 species
cataloged within two global biodiversity hotspots: Atlantic Forest and Cerrado, the Brazilian …

Considerations to Be Taken When Carrying Out Medicinal Plant Research—What We Learn from an Insight into the IC50 Values, Bioavailability and Clinical Efficacy …

M Abdel-Tawab - Pharmaceuticals, 2021 - mdpi.com
Medicinal plants represent a big reservoir for discovering new drugs against all kinds of
diseases including inflammation. In spite the large number of promising anti-inflammatory …

Interaction of 4′-methylflavonoids with biological membranes, liposomes, and human albumin

A Włoch, P Strugała-Danak, H Pruchnik… - Scientific Reports, 2021 - nature.com
The aim of the study was to compare the impact of three synthesized chemical compounds
from a group of methylated flavonoids, ie 2′-hydroxy-4-methylchalcone (3), 4 …

Theobroma cacao and Theobroma grandiflorum: Botany, Composition and Pharmacological Activities of Pods and Seeds

E Jean-Marie, W Jiang, D Bereau, JC Robinson - Foods, 2022 - mdpi.com
Cocoa and cupuassu are evergreen Amazonian trees belonging to the genus Theobroma,
with morphologically distinct fruits, including pods and beans. These beans are generally …

Tissue distribution of oleocanthal and its metabolites after oral ingestion in rats

A López-Yerena, A Vallverdú-Queralt, O Jáuregui… - Antioxidants, 2021 - mdpi.com
Claims for the potential health benefits of oleocanthal (OLC), a dietary phenolic compound
found in olive oil, are based mainly on in vitro studies. Little is known about the tissue …