Virtually all domains of cognitive function require the integration of distributed neural activity.
Network analysis of human brain connectivity has consistently identified sets of regions that …

Contrary to assumptions that changes in brain networks are possible only during crucial
periods of development, research in the past decade has supported the idea of a …

1. Background The El Escorial criteria for the diagnosis of Amyotrophic Lateral Sclerosis
(ALS) were initially published in 1994 (Brooks, 1994) and revised in 2000 (Brooks et al …

Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder of
the motor neurons in the motor cortex, brainstem and spinal cord. A combination of upper …

While neurodegenerative diseases are characterized by steady degeneration over relatively
long timelines, it is widely believed that the early stages are the most promising for …

In the past two decades, structural and functional neuroimaging findings have greatly
modified longstanding notions regarding the pathophysiology of amyotrophic lateral …

Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease, with large
variation in survival between patients. Currently, it remains rather difficult to predict survival …

Amyotrophic lateral sclerosis as a system failure is a concept supported by the finding of
consistent extramotor as well as motor cerebral pathology. The functional correlates of the …

Objective Damage to the cerebral tissue structural connectivity associated with amyotrophic
lateral sclerosis (ALS), which extends beyond the motor pathways, can be visualised by …