Non-coding RNAs in disease: from mechanisms to therapeutics
K Nemeth, R Bayraktar, M Ferracin… - Nature Reviews Genetics, 2024 - nature.com
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
[HTML][HTML] Biomarkers in cancer detection, diagnosis, and prognosis
S Das, MK Dey, R Devireddy, MR Gartia - Sensors, 2023 - mdpi.com
Biomarkers are vital in healthcare as they provide valuable insights into disease diagnosis,
prognosis, treatment response, and personalized medicine. They serve as objective …
prognosis, treatment response, and personalized medicine. They serve as objective …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …
physiology and pathology in living systems, making significant contributions to life science …
Photocleavable Ortho-Nitrobenzyl-Protected DNA Architectures and Their Applications
This review article introduces mechanistic aspects and applications of photochemically
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …
Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours
Background In this first-in-human, Phase 1 study of a microRNA-based cancer therapy, the
recommended Phase 2 dose (RP2D) of MRX34, a liposomal mimic of microRNA-34a (miR …
recommended Phase 2 dose (RP2D) of MRX34, a liposomal mimic of microRNA-34a (miR …
A new era in functional genomics screens
L Przybyla, LA Gilbert - Nature Reviews Genetics, 2022 - nature.com
The past 25 years of genomics research first revealed which genes are encoded by the
human genome and then a detailed catalogue of human genome variation associated with …
human genome and then a detailed catalogue of human genome variation associated with …
[HTML][HTML] MicroRNA: A signature for cancer progression
BM Hussen, HJ Hidayat, A Salihi, DK Sabir… - Biomedicine & …, 2021 - Elsevier
MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …
control expression of genes by targeting mRNAs. miRNA alterations partake in the …
MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies
As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in
cancer development. Since the discovery of the identity and clinical functions of miRNAs …
cancer development. Since the discovery of the identity and clinical functions of miRNAs …
Stimuli-responsive metal–organic framework nanoparticles for controlled drug delivery and medical applications
Z Zhou, M Vázquez-González, I Willner - Chemical Society Reviews, 2021 - pubs.rsc.org
Stimuli-responsive metal–organic framework nanoparticles, NMOFs, provide a versatile
platform for the controlled release of drugs and biomedical applications. The porous …
platform for the controlled release of drugs and biomedical applications. The porous …