Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …

Butyrylcholinesterase is a serine hydrolase that catalyzes the hydrolysis of esters in the
body. Unlike its sister enzyme acetylcholinesterase, butyrylcholinesterase has a broad …

Out of several heterocyclic templates, the use of a Benzimidazole (BZ) scaffold is immensely
observed. This fused heterocycle comprises two ring nitrogen atoms placed at 1st and 3rd …

Diabetes mellitus (DM), a complicated metabolic disorder, is due to insensitivity to insulin
function or reduction in insulin secretion, which results in postprandial hyperglycemia. α …

N-aryl pyrazoles are important building blocks in many biologically active compounds,
natural products, pharmaceuticals, and industries. It is an important moiety of various drugs …

Alzheimer's disease (AD) is the most devastating and progressive neurodegenerative
disease in middle to elder aged people, which can be exacerbated by lifestyle factors …

α-Haloketones play an essential role in the synthesis of complex N-, S-, O-heterocycles; of
which some exhibit a remarkable biological activity. Research further illustrated that α-bromo …

The fused heterocyclic ring system has been recognized as a privileged structure that is
used as a template in medicinal chemistry for drug discovery. Benzimidazole is one of the …

In this work, a novel series of arylisoxazole‐phenylpiperazines were designed, synthesized,
and evaluated toward acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Our …

Benzimidazole and benzoxazole derivatives are included in the category of medical drugs in
a wide range of areas such as anticancer, anticoagulant, antihypertensive, anti …