Challenges and promise at the interface of metaproteomics and genomics: an overview of recent progress in metaproteogenomic data analysis

H Schiebenhoefer, T Van Den Bossche… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The study of microbial communities based on the combined analysis of
genomic and proteomic data–called metaproteogenomics–has gained increased research …

Current progress and critical challenges to overcome in the bioinformatics of mass spectrometry-based metaproteomics

N Miura, S Okuda - Computational and Structural Biotechnology Journal, 2023 - Elsevier
Metaproteomics is a relatively young field that has only been studied for approximately 15
years. Nevertheless, it has the potential to play a key role in disease research by elucidating …

Limited carbon cycling due to high-pressure effects on the deep-sea microbiome

C Amano, Z Zhao, E Sintes, T Reinthaler… - Nature …, 2022 - nature.com
Deep-sea microbial communities are exposed to high-pressure conditions, which has a
variable impact on prokaryotes depending on whether they are piezophilic (that is, pressure …

Unipept 4.0: functional analysis of metaproteome data

R Gurdeep Singh, A Tanca, A Palomba… - Journal of proteome …, 2018 - ACS Publications
Unipept (https://unipept. ugent. be) is a web application for metaproteome data analysis, with
an initial focus on tryptic-peptide-based biodiversity analysis of MS/MS samples. Because …

A complete and flexible workflow for metaproteomics data analysis based on MetaProteomeAnalyzer and Prophane

H Schiebenhoefer, K Schallert, BY Renard, K Trappe… - Nature protocols, 2020 - nature.com
Metaproteomics, the study of the collective protein composition of multi-organism systems,
provides deep insights into the biodiversity of microbial communities and the complex …

Database-independent de novo metaproteomics of complex microbial communities

HBC Kleikamp, M Pronk, C Tugui, LG da Silva… - Cell Systems, 2021 - cell.com
Metaproteomics has emerged as one of the most promising approaches for determining the
composition and metabolic functions of complete microbial communities. Conventional …

Transcriptomic-proteomic integration: A powerful synergy to elucidate the mechanisms of meat spoilage in the cold chain

AP Bassey, K Ye, C Li, G Zhou - Trends in Food Science & Technology, 2021 - Elsevier
Background The ubiquity and diversity of spoilage microorganisms in the cold chain have
caused incessant spoilage occurrences, resulting in significant economic losses to food …

Progress and challenges in ocean metaproteomics and proposed best practices for data sharing

MA Saito, EM Bertrand, ME Duffy… - Journal of proteome …, 2019 - ACS Publications
Ocean metaproteomics is an emerging field enabling discoveries about marine microbial
communities and their impact on global biogeochemical processes. Recent ocean …

Metaproteomic and metabolomic approaches for characterizing the gut microbiome

DL Peters, W Wang, X Zhang, Z Ning, J Mayne… - …, 2019 - Wiley Online Library
The gut microbiome has been shown to play a significant role in human healthy and
diseased states. The dynamic signaling that occurs between the host and microbiome is …

The landscape and perspectives of the human gut metaproteomics

Z Sun, Z Ning, D Figeys - Molecular & Cellular Proteomics, 2024 - ASBMB
The human gut microbiome is closely associated with human health and diseases.
Metaproteomics has emerged as a valuable tool for studying the functionality of the gut …