Intraoperative imaging modalities and compensation for brain shift in tumor resection surgery

S Bayer, A Maier, M Ostermeier… - International journal of …, 2017 - Wiley Online Library
Intraoperative brain shift during neurosurgical procedures is a well‐known phenomenon
caused by gravity, tissue manipulation, tumor size, loss of cerebrospinal fluid (CSF), and use …

Modelling brain deformations for computer‐integrated neurosurgery

K Miller, A Wittek, G Joldes, A Horton… - International Journal …, 2010 - Wiley Online Library
In this review paper we discuss Intelligent Systems for Medicine Laboratory's contributions to
mathematical and numerical modelling of brain deformation behaviour for neurosurgical …

Realistic simulation of the 3-D growth of brain tumors in MR images coupling diffusion with biomechanical deformation

O Clatz, M Sermesant, PY Bondiau… - IEEE transactions on …, 2005 - ieeexplore.ieee.org
We propose a new model to simulate the three-dimensional (3-D) growth of glioblastomas
multiforma (GBMs), the most aggressive glial tumors. The GBM speed of growth depends on …

Robust nonrigid registration to capture brain shift from intraoperative MRI

O Clatz, H Delingette, IF Talos, AJ Golby… - IEEE transactions on …, 2005 - ieeexplore.ieee.org
We present a new algorithm to register 3-D preoperative magnetic resonance (MR) images
to intraoperative MR images of the brain which have undergone brain shift. This algorithm …

Patient-specific model of brain deformation: Application to medical image registration

A Wittek, K Miller, R Kikinis, SK Warfield - Journal of biomechanics, 2007 - Elsevier
This contribution presents finite element computation of the deformation field within the brain
during craniotomy-induced brain shift. The results were used to illustrate the capabilities of …

Non-rigid alignment of pre-operative MRI, fMRI, and DT-MRI with intra-operative MRI for enhanced visualization and navigation in image-guided neurosurgery

N Archip, O Clatz, S Whalen, D Kacher, A Fedorov… - Neuroimage, 2007 - Elsevier
Objective: The usefulness of neurosurgical navigation with current visualizations is seriously
compromised by brain shift, which inevitably occurs during the course of the operation …

Simulation of brain tumors in MR images for evaluation of segmentation efficacy

M Prastawa, E Bullitt, G Gerig - Medical image analysis, 2009 - Elsevier
Obtaining validation data and comparison metrics for segmentation of magnetic resonance
images (MRI) are difficult tasks due to the lack of reliable ground truth. This problem is even …

High-speed nonlinear finite element analysis for surgical simulation using graphics processing units

ZA Taylor, M Cheng, S Ourselin - IEEE transactions on medical …, 2008 - ieeexplore.ieee.org
The use of biomechanical modelling, especially in conjunction with finite element analysis,
has become common in many areas of medical image analysis and surgical simulation …

A meshless Total Lagrangian explicit dynamics algorithm for surgical simulation

A Horton, A Wittek, GR Joldes… - International journal for …, 2010 - Wiley Online Library
A method is presented for computing deformation of very soft tissue. The method is
motivated by the need for simple, automatic model creation for real‐time simulation. The …

Suite of finite element algorithms for accurate computation of soft tissue deformation for surgical simulation

GR Joldes, A Wittek, K Miller - Medical image analysis, 2009 - Elsevier
Real time computation of soft tissue deformation is important for the use of augmented reality
devices and for providing haptic feedback during operation or surgeon training. This …