Temperature-responsive nano-biomaterials from genetically encoded farnesylated disordered proteins

MS Hossain, Z Zhang, S Ashok, AR Jenks… - ACS Applied Bio …, 2022 - ACS Publications
Despite broad interest in understanding the biological implications of protein farnesylation in
regulating different facets of cell biology, the use of this post-translational modification to …

Genetically encoded cholesterol-modified polypeptides

D Mozhdehi, KM Luginbuhl, M Dzuricky… - Journal of the …, 2019 - ACS Publications
Biological systems use post-translational modifications (PTMs) to control the structure,
location, and function of proteins after expression. Despite the ubiquity of PTMs in biology …

Genetically Engineered Liposwitch-Based Nanomaterials

MS Hossain, A Wang, S Anika, Z Zhang… - …, 2024 - ACS Publications
Fusion of intrinsically disordered and globular proteins is a powerful strategy to create
functional nanomaterials. However, the immutable nature of genetic encoding restricts the …

Genetically Encoded Inverse Bolaamphiphiles

MS Hossain, X Liu, TI Maynard, D Mozhdehi - Biomacromolecules, 2019 - ACS Publications
Develo** new protein-based materials with a programmable assembly is of great scientific
interest and technological importance. Inspired by nature's use of post-translational …

Recombinantly Engineered Polypeptides for Drug Delivery

KM Luginbuhl - 2017 - search.proquest.com
Novel drug delivery methods aims to improve the therapeutic efficacy by enhancing the
molecule's pharmacokinetic profile as well as increasing its accumulation at the target size …